Results 131 to 140 of about 1,530,143 (402)

Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]

, 1982
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux, BA Kihlman, C Cremer, C Cremer, C Cremer, C Cremer, C Wollenberg, C Zorn, C Zorn, C. Cremer, DE Barton, DE Comings, DE Comings, E Therman, F Vogel, FE Fosse Del, H Kato, H. Baumann, HD Hager, JW Gray, K Church, K Nilsson, L Avivi, L Hens, L Hens, L. Hens, LL Deaven, M Ray, M Schmid, M. Kirsch-Volders, S Brenner, T Caspersson, T Cremer, T Cremer, T. Cremer, T. Schneider, Th Boveri, W Sauerbier, Y Moroi   +38 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Heterogeneity in telomere length of human chromosomes.

Human Molecular Genetics, 1996
Vertebrate chromosomes terminate in variable numbers of T2AG3 nucleotide repeats. In order to study telomere repeats at individual chromosomes, we developed novel, quantitative fluorescence in situ hybridization procedures using labeled (C3TA2)3 peptide ...
P. Lansdorp, N. Verwoerd, F. M. Rijke, V. Dragowska, M. Little, R. Dirks, A. Raap, H. Tanke   +7 more
semanticscholar   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Chinese hamster genome sequenced from sorted chromosomes

Nature Biotechnology, 2013
volume 31 NumBeR 8 AuGuST 2013 nature biotechnology Current NGS technology yields shortread sequences typically in the range of 100–500 bp, so that common repeats cannot be assembled and the precise location of duplicated sequences is likely to be ...
Karina Brinkrolf, O. Rupp, Holger Laux, Florian Kollin, W. Ernst, Burkhard Linke, R. Kofler, Sandrine Romand, F. Hesse, W. Budach, S. Galosy, D. Müller, T. Noll, J. Wienberg, T. Jostock, M. Leonard, J. Grillari, A. Tauch, A. Goesmann, B. Helk, J. Mott, A. Pühler, N. Borth   +22 more
semanticscholar   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Chromosomes of the experimental hybrid of Crussostrea virginica Gmelin 1791 and Crussostreu rhizophorue Guilding 1828 (Pseudolamellibranchiata: Ostreidae)

Ciencias Marinas, 1998
The cytogenetic study of the interspecific larval hybrid of Crassostrau virginica and Crassostrea rhizophorae has been conducted. The chromosome complements in all the types of hybrids assayed were integrated in a normal way to form the zygote and the ...
F Rodríguez-Romero, M Gascas-Montes-Oca, M Gascas-Montes-Oca   +2 more
doaj   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, Volume 15, Issue 7, Page 1144-1158, July 2025.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Comparison of the karyotypes of the central and southern populations of the northern anchovy Engraufis mordax, girard 1854 (engraulidae, pisces)

Ciencias Marinas, 1996
The northern anchovy Engraulis mordax is an important fishery resource. The karyotypes of the central and southern populations of the northern anchovy, as well as their C-banding patterns were studied as potential genetic markers.
M Uribe-Alcocer, N Valdés-Morales, P Díaz-Jaimes, Y Hornelas-Orozco   +3 more
doaj   +1 more source

FINE STRUCTURE OF CHROMOSOMES [PDF]

, 1956
Berwind P. Kaufmann, Deepesh N. De
openalex   +1 more source