Results 151 to 160 of about 1,562,582 (397)

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

The Human Intrinsic Factor-Vitamin B12 Receptor,Cubilin: Molecular Characterization and Chromosomal Mapping of the Gene to 10p Within the Autosomal Recessive Megaloblastic Anemia (MGA1) Region [PDF]

, 1998
Renata Kozyraki, Mette Kristiansen, Asli Silahtaroglu, Claus Hansen, Christian Jacobsen, Niels Tommerup, P Verroust, Søren K. Moestrup   +7 more
openalex   +1 more source

Building a eukaryotic chromosome arm by de novo design and synthesis [PDF]

, 2023
Shuangying Jiang, Zhouqing Luo, Jie Wu, Yu Kang, Shijun Zhao, Zelin Cai, Wenfei Yu, Hui Wang, Li Cheng, Zhenzhen Liang, Hui Gao, Marco Monti, Daniel Schindler, Linsen Huang, Cheng Zeng, Weimin Zhang, Chun Zhou, Yuanwei Tang, Tianyi Li, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Qiao Zhao, Junbiao Dai   +23 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Cell, 1993
M. MacDonald, C. Ambrose, M. Duyao, R. Myers, Carol S. Lin, L. Srinidhi, G. Barnes, Sherryl A. M. Taylor, M. James, Nicolet Groot, Heather MacFarlane, B. Jenkins, M. Anderson, N. Wexler, J. Gusella, G. Bates, S. Baxendale, H. Hummerich, S. Kirby, M. North, S. Youngman, R. Mott, G. Zehetner, Z. Sedlacek, A. Poustka, A. Frischauf, H. Lehrach, A. Buckler, D. Church, L. Doucette-Stamm, M. O’Donovan, Laura Riba-Ramírez, Manish S. Shah, V. Stanton, S. Strobel, K. Draths, Jennifer L. Wales, P. Dervan, D. Housman, M. Altherr, R. Shiang, L. Thompson, T. Fielder, J. Wasmuth, D. Tagle, J. Valdes, Lon Elmer, M. Allard, L. Castilla, M. Swaroop, K. Blanchard, F. Collins, R. Snell, T. Holloway, Kathleen Gillespie, N. Datson, D. Shaw, P. Harper   +57 more
semanticscholar   +1 more source

Condiciones óptimas de cultivo de linfocitos y análisis parcial del cariotipo de la tortuga cabezona, Caretta caretta (Testudines: Cheloniidae) en Santa Marta, Caribe Colombiano

Revista de Biología Tropical, 2008
En los últimos años se ha registrado una disminución importante en el número de individuos de la tortuga marina Caretta caretta anidantes en el Caribe colombiano, situación que pone en evidencia la posibilidad de su extinción a mediano plazo.
Ellie Ann López, Javier Hernández-Fernández, Jaime Bernal-Villegas   +2 more
doaj  

Phosphorylation-induced Rearrangement of the Histone H3 NH2-terminal Domain during Mitotic Chromosome Condensation [PDF]

, 1999
Debra M. Sauvé, Hilary Anderson, Jill Ray, William M. James, Michel Roberge   +4 more
openalex   +1 more source

The CENP-F-like Proteins HCP-1 and HCP-2 Target CLASP to Kinetochores to Mediate Chromosome Segregation [PDF]

, 2005
Iain M. Cheeseman, Ian MacLeod, John R. Yates, Karen Oegema, Arshad Desai   +4 more
openalex   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Spatial organization of chromatin domains and compartments in single chromosomes

Science, 2016
Siyuan S Wang, Jun-Han Su, Brian J. Beliveau, B. Bintu, J. Moffitt, Chao-ting Wu, X. Zhuang   +6 more
semanticscholar   +1 more source