Results 261 to 270 of about 488,806 (311)
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Cytogenetic and Genome Research, 2005
The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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Journal of Cell Science, 1977
ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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Chromosome imprinting and the mammalian X chromosome
Nature, 1975Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
H S, Chandra, S W, Brown
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The human Y chromosome: a masculine chromosome
Current Opinion in Genetics & Development, 2006Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J, Noordam, Sjoerd, Repping
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Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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Chromosom I, Chromosom II, Chromosom III, Chromosom IV; [ca. 1950]
2023Auf Papier mit ...
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Chromosome 18 replaced by two ring chromosomes of chromosome 18 origin
Human Genetics, 2003We here describe the first example of the replacement of an autosome by two ring chromosomes originating from the missing chromosome, presented in a patient with a single chromosome 18 and two additional ring chromosomes. Detailed fluorescence in situ hybridization (FISH) analysis revealed the chromosome 18 origin of both ring chromosomes and ...
K, Miller +6 more
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2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012
Karyotyping is the process of arranging pairs of the chromosomes in an order to examine chromosomal abnormalities which are the causes for Birth Defects. The overlapping and touching chromosomes of input metaphase spread images should be segmented and disentangled for this process.
Nirmala Madian, K. B. Jayanthi
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Karyotyping is the process of arranging pairs of the chromosomes in an order to examine chromosomal abnormalities which are the causes for Birth Defects. The overlapping and touching chromosomes of input metaphase spread images should be segmented and disentangled for this process.
Nirmala Madian, K. B. Jayanthi
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Chromosome Conformation Capture of Mitotic Chromosomes
2023Despite more than a century of intensive study of mitotic chromosomes, their three-dimensional organization remains enigmatic. The last decade established Hi-C as a method of choice for study of spatial genome-wide interactions. Although its utilization has been focused mainly on studying genomic interactions in interphase nuclei, the method can be ...
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Sex Chromosomes and Sex Chromosome Abnormalities
Clinics in Laboratory Medicine, 2011This article focuses on constitutional sex chromosome abnormalities detected by conventional cytogenetics and fluorescence in situ hybridization. The author discusses the two general classifications of abnormalities: numerical and structural. Also included are descriptions of unique aspects of X and Y chromosomes, technological advances in detection ...
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