Triple-Helical DNA in Drosophila Heterochromatin
Cells, 2018 Polynucleotide chains obeying Watson-Crick pairing are apt to form non-canonical complexes such as triple-helical nucleic acids. From early characterization in vitro, their occurrence in vivo has been strengthened by increasing evidence, although most ...
Eduardo Gorab
doaj +1 more source
Characterization of two marker chromosomes in a patient with acute nonlymphocytic leukemia by two-color fluorescence in situ hybridization [PDF]
, 1993 A patient with acute nonlymphocytic leukemia (ANLL), M5b according to French-American-British (FAB) classification, showed monosomy 16, an extra 1p−, and a 21q+. These derivative chromosomes could not be defined by GTG-banding.
Speicher, Michael R. +5 more
core +1 more source
Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis
eLife, 2019 To ensure proper segregation during mitosis, chromosomes must be efficiently captured by spindle microtubules and subsequently aligned on the mitotic spindle.
Alexander JR Booth +6 more
doaj +1 more source
Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. [PDF]
, 2005 Chromosomes are highly organized and compartmentalized in cell nuclei. The analysis of their position is a powerful way to monitor genome organization in different cell types and states.
Foster, H +7 more
core +1 more source
Architecture of metaphase chromosomes and chromosome scaffolds. [PDF]
The Journal of cell biology, 1983 We have developed procedures for depositing intact mitotic chromosomes and isolated residual scaffolds on electron microscope grids at controlled and reproducible levels of compaction. The chromosomes were isolated using a recently developed aqueous method. Our study has addressed two different aspects of chromosome structure.
Earnshaw, William C. +1 more
openaire +3 more sources
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes [PDF]
, 2005 Studies of higher-order chromatin arrangements are an essential part of ongoing attempts to explore changes in epigenome structure and their functional implications during development and cell differentiation.
Kreth Gregor +54 more
core +1 more source
Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the w chromosome [PDF]
, 2014 We used a comparative approach spanning three species and 90 million years to study the evolutionary history of the avian sex chromosomes. Using whole transcriptomes, we assembled the largest cross-species dataset of W-linked coding content to date.
Wright, Alison E +9 more
core +1 more source
Comparative Cytogenetics, 2010 The fresh water polyp Hydra L., 1758 (Cnidaria, Hydrozoa) plays a key role as a model organism in modern evolutionary and developmental biology. A complete genome sequence has been published recently for Hydra magnipapillata Ito, 1947 and molecular ...
B Anokhin, G Hemmrich-Stanisak, T Bosch
doaj +1 more source
Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA
Molecules, 2022 The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard +3 more
doaj +1 more source
Chromosomal rearrangements in cattle and pigs revealed by chromosome microdissection and chromosome painting [PDF]
Genetics Selection Evolution, 2003 A pericentric inversion of chromosome 4 in a boar, as well as a case of (2q-;5p+) translocation mosaicism in a bull were analysed by chromosome painting using probes generated by conventional microdissection. For the porcine inversion, probes specific for p arms and q arms were produced and hybridised simultaneously on metaphases of a heterozygote ...
Pinton, Alain +2 more
openaire +7 more sources