Results 341 to 350 of about 1,562,582 (397)
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Chromosome Conformation Capture of Mitotic Chromosomes

2023
Despite more than a century of intensive study of mitotic chromosomes, their three-dimensional organization remains enigmatic. The last decade established Hi-C as a method of choice for study of spatial genome-wide interactions. Although its utilization has been focused mainly on studying genomic interactions in interphase nuclei, the method can be ...
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The human Y chromosome: a masculine chromosome

Current Opinion in Genetics & Development, 2006
Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J, Noordam, Sjoerd, Repping
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Chromosomal Instability

Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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Age and Chromosomes

Nature, 1966
RECENTLY, I carried out chromosome analyses and sex chromatin determinations on ten patients—five females and five males—between 63 and 91 years old. The organic status of these individuals was variable, and all were ill in some way. Nevertheless, the results obtained in this investigation were reasonably uniform; their chromosomes and Barr bodies ...
P A, Jacobs, W M, Court BROWN
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Sex Chromosomes in Land Plants

Annual Review of Plant Biology, 2011
Ray Ming, Susanne S Renner
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Sex Chromosomes and Sex Chromosome Abnormalities

Clinics in Laboratory Medicine, 2011
This article focuses on constitutional sex chromosome abnormalities detected by conventional cytogenetics and fluorescence in situ hybridization. The author discusses the two general classifications of abnormalities: numerical and structural. Also included are descriptions of unique aspects of X and Y chromosomes, technological advances in detection ...
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[Chromosomes and chromosome disorders].

Nordisk medicin, 1990
The risk of bearing a child with chromosomal defects increases once the mother reaches the age of 35; the principal indication for chromosomal examination of the fetus is that the pregnant woman is "older". Chromosomal examination of new-born babies is indicated if it is suspected that dysmorphic features may depend on cytogenetic deviation.
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The chromosomes in hematology

Cancer Genetics and Cytogenetics, 1981
Abstract Chromosome studies in hematological disorders made rapid and significant advances following the introduction of banding techniques and the most salient features of these studies are succinctly reported in this Review. Considering the consistency of the chromosome anomalies first, it appears that about 50% of the acute leukemias do not present
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