Results 341 to 350 of about 1,551,359 (398)
DNA methylation profiling of human chromosomes 6, 20 and 22
Nature Genetics, 2006 DNA methylation is the most stable type of epigenetic modification modulating the transcriptional plasticity of mammalian genomes. Using bisulfite DNA sequencing, we report high-resolution methylation profiles of human chromosomes 6, 20 and 22, providing
Rene Cortese, Kevin L Howe, Stephan Beck
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Origins and functional evolution of Y chromosomes across mammals
Nature, 2014Diego Cortez, Ray M Marin, Paul D Waters
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Telomeres: protecting chromosomes against genome instability
Nature Reviews Molecular Cell Biology, 2010 Jan Karlseder
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Chromosome imprinting and the mammalian X chromosome [PDF]
Nature, 1975 Chromosome imprinting is the process by which one of two genetically homologous chromosomes is predetermined to function differently from the other at a subsequent stage in development. In the coccid insects, imprinting occurs in the egg, at the time of fertilisation; it probably occurs at the same time and site in mammals, and possibly also in Sciara.
Spencer W. Brown, H. Sharat Chandra
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Cytogenetic and Genome Research, 2005
The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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The term “chromosomics” is introduced to draw attention to the three-dimensional morphological changes in chromosomes that are essential elements in gene regulation. Chromosomics deals with the plasticity of chromosomes in relation to the three-dimensional positions of genes, which affect cell function in a developmental and tissue-specific manner ...
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Current Opinion in Oncology, 2004
This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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This review discusses numerical and structural chromosomal instability in cancer cells and its possible etiologies, highlighting the recent literature.Defects in chromosomal segregation, telomere stability, and the DNA damage response play significant roles in chromosomal instability in cancer.The pace of discoveries into the biologic basis of ...
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Journal of Cell Science, 1977
ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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ABSTRACT 1986 was a celebration year for lampbrush chromosomes (LBCs), marked by the publication of Callan’s comprehensive and authoritative book on these structures. My commentary begins where Callan’s book ends, standing on tiptoe beside a large and rather neat assembly of well-established facts, principles and hypotheses, and trying ...
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Sex Chromosomes in Land Plants
Annual Review of Plant Biology, 2011Ray Ming, Susanne S Renner
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Nature, 1966
RECENTLY, I carried out chromosome analyses and sex chromatin determinations on ten patients—five females and five males—between 63 and 91 years old. The organic status of these individuals was variable, and all were ill in some way. Nevertheless, the results obtained in this investigation were reasonably uniform; their chromosomes and Barr bodies ...
W. M. Court Brown, Patricia A. Jacobs
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RECENTLY, I carried out chromosome analyses and sex chromatin determinations on ten patients—five females and five males—between 63 and 91 years old. The organic status of these individuals was variable, and all were ill in some way. Nevertheless, the results obtained in this investigation were reasonably uniform; their chromosomes and Barr bodies ...
W. M. Court Brown, Patricia A. Jacobs
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The human Y chromosome: a masculine chromosome
Current Opinion in Genetics & Development, 2006Once considered to be a genetic wasteland of no scientific interest beyond sex determination, the human Y chromosome has made a significant comeback in the past few decades and is currently implicated in multiple diseases, including spermatogenic failure - absent or very low levels of sperm production.
Michiel J. Noordam, Sjoerd Repping
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