Results 51 to 60 of about 1,562,582 (397)

The self-organization of genomes [PDF]

, 2010
Menzerath-Altmann law is a general law of human language stating, for instance, that the longer a word, the shorter its syllables. With the metaphor that genomes are words and chromosomes are syllables, we examine if genomes also obey the law.
Ferrer Cancho, Ramon, Forns Fradera, Núria   +1 more
core   +2 more sources

SCREENING FOR BIOMORPHOLOGICAL AND CYTOGENETIC FEATURES OF POLEMONIUM CAERULEUM L. AFTER COLCHICINE APPLICATION

Siberian Journal of Life Sciences and Agriculture, 2023
Background. Currently, it is quite relevant in breeding to create varieties with high yields of raw materials and the content of biologically active compounds. This work aim is to identify promising forms of P. caeruleum L. is for further inclusion in
Firdaus M. Khazieva, Irina V. Basalaeva, Elena A. Konyaeva, Alla E. Burova, Tatyana Е. Samatadze   +4 more
doaj   +1 more source

A Chromosome RNAissance [PDF]

Cell, 2002
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
Dernburg, Abby F., Karpen, Gary H.
openaire   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments [PDF]

, 1982
In 1885 Carl Rabl published his theory on the internal structure of the interphase nucleus. We have tested two predictions of this theory in fibroblasts grown in vitro from a female Chinese hamster, namely (1) the Rabl-orientation of interphase ...
C Cremer, C Cremer, C Cremer, C Cremer, C Cremer, C Rabl, C Zorn, C Zorn, C. Cremer, C. Zorn, DE Comings, DE Comings, DM Pardoll, E. K. Luedtke, F Vogel, H Hoehn, H Zankl, H. Baumann, K Sperling, K Sperling, K Sperling, K. Sperling, KD Zang, L Avivi, L Hens, M Kirsch-Volders, M Kirsch-Volders, R Berezney, T Cremer, T. Cremer, Th Boveri, Th Boveri, V. Teuber, W Schnedl, Y Moroi   +34 more
core   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Why genes evolve faster on secondary chromosomes in bacteria [PDF]

, 2010
In bacterial genomes composed of more than one chromosome, one replicon is typically larger, harbors more essential genes than the others, and is considered primary.
Cooper, Vaughn S., Hatcher, Philip J., Vohr, Samuel H., Wrocklage, Sarah C.   +3 more
core   +1 more source

Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]

, 1982
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux, BA Kihlman, C Cremer, C Cremer, C Cremer, C Cremer, C Wollenberg, C Zorn, C Zorn, C. Cremer, DE Barton, DE Comings, DE Comings, E Therman, F Vogel, FE Fosse Del, H Kato, H. Baumann, HD Hager, JW Gray, K Church, K Nilsson, L Avivi, L Hens, L Hens, L. Hens, LL Deaven, M Ray, M Schmid, M. Kirsch-Volders, S Brenner, T Caspersson, T Cremer, T Cremer, T. Cremer, T. Schneider, Th Boveri, W Sauerbier, Y Moroi   +38 more
core   +1 more source

Cytogenetic abnormalities in patients with hematological malignancies in Lahore city, Pakistan

Brazilian Journal of Biology, 2021
Hematological and hematopoietic cells malignancies of the genes and hematopoietic cells are associated with the genetic mutation, often at the chromosomal level.
U. A. Awan, N. Farooq, A. Sarwar, H. M. S. Jehangir, M. S. Hashmi, M. Alamgir, F. Waheed, M. Khurram, H. Ahmed, A. A. Khattak, M. S. Afzal   +10 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source