Results 101 to 110 of about 10,167,326 (383)

Undiagnosed mood disorders and sleep disturbances in primary care patients with chronic musculoskeletal pain. [PDF]

open access: yes, 2013
Objective. The study aims to determine the prevalence of undiagnosed comorbid mood disorders in patients suffering chronic musculoskeletal pain in a primary care setting and to identify sleep disturbances and other associated factors in these ...
Alejandro Salazar   +11 more
core   +2 more sources

Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6

open access: yesJournal of Neuroinflammation, 2011
Background Chronic neurodegeneration comprises an inflammatory response but its contribution to the progression of disease remains unclear. We have previously shown that microglial cells are primed by chronic neurodegeneration, induced by the ME7 strain ...
Cunningham Colm   +2 more
doaj   +1 more source

Improving chronic illness care: translating evidence into action.

open access: yesHealth Affairs, 2001
The growing number of persons suffering from major chronic illnesses face many obstacles in coping with their condition, not least of which is medical care that often does not meet their needs for effective clinical management, psychological support, and
E. Wagner   +5 more
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Is traumatic and non-traumatic neck pain associated with brain alterations? : a systematic review [PDF]

open access: yes, 2017
Background: Chronic neck pain affects 50% - 85% of people who have experienced an acute episode. This transition and the persistence of chronic complaints are believed to be mediated by brain alterations among different central mechanisms.
Caeyenberghs, Karen   +5 more
core  

Effects of online hemodiafiltration on anemia and nutritional status in chronic hemodialysis patients

open access: yesKidney Research and Clinical Practice, 2020
Background : : Online hemodiafiltration (OL-HDF) offers considerable advantages in clearance of molecules of various sizes. However, evidence of clinical effects of OL-HDF is scarce in Korea.
Yu Ho Lee   +14 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Towards a science and practice of resilience in the face of pain [PDF]

open access: yes, 2017
The primary objective of this paper is to discuss how a resilience approach to (chronic) pain may advance our current understanding of (mal)adaptation to pain.
Alschuler   +140 more
core   +3 more sources

The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study

open access: yesEnvironmental Health, 2011
Background Urinary kidney injury molecule 1 is a recently discovered early biomarker for renal damage that has been proven to be correlated to urinary cadmium in rats.
Dewitte Harrie   +10 more
doaj   +1 more source

Design manual: Oxygen Thermal Test Article (OTTA) [PDF]

open access: yes
The characteristics of a cryogenic tank for storing liquid hydrogen, nitrogen, oxygen, methane, or helium for an extended period of time with minimum losses are discussed.
Baese, C. L.   +2 more
core   +1 more source

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