Results 151 to 160 of about 10,167,326 (383)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

open access: yes, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Azza Azza Abdel-Aziz   +5 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Evaluation of the Conrad N. Hilton Foundation Chronic Homelessness Initiative: 2015 [PDF]

open access: yes, 2015
Under a September 2011 contract with the Conrad N. Hilton Foundation, Abt Associates has been conducting an evaluation of the Hilton Foundation's Chronic Homelessness Initiative, with the goal of answering the overarching question: Is the Chronic ...

core  

COPD disease severity and innate immune response to pathogen-associated molecular patterns

open access: yesInternational Journal of COPD, 2016
Vincent S Fan,1,2 Sina A Gharib,2,3 Thomas R Martin,1,2 Mark M Wurfel2 1VA Puget Sound Health Care System, Seattle, WA, USA; 2Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Washington, Seattle WA, USA ...
Fan VS, Gharib SA, Martin TR, Wurfel MM
doaj  

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

CHRONIC HEPATITIS

open access: yesBritish Medical Bulletin, 1972
The term chronic hepatitis is used to include prolonged inflammation of the liver following an attack of acute viral hepatitis, either icteric or anicteric, or chronic active hepatitis, of unknown aetiology. We accept the Fogarty proceedings definition of chronic hepatitis as inflammation of the liver for six months or more, although the duration of ...
openaire   +4 more sources

Differentiation and Protective Capacity of Virus-Specific CD8 [PDF]

open access: yes, 2017
Noroviruses can establish chronic infections with active viral shedding in healthy humans but whether persistence is associated with adaptive immune dysfunction is unknown.
Bengsch, Bertram   +12 more
core   +1 more source

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