Results 51 to 60 of about 10,167,326 (383)

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

Journal of Clinical Investigation, 2003
Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism in peripheral tissues. Increasing evidence from human population studies and animal research has established correlative as well as causative links ...
Haiyan Xu, Glenn Barnes, Qing Yang, G. Tan, Daseng Yang, C. Chou, Jason Sole, A. Nichols, J. Ross, L. Tartaglia, Hong Chen   +10 more
semanticscholar   +1 more source

Chronic Anticoagulation in Chronic Kidney Disease∗

Journal of the American College of Cardiology, 2014
Bleeding in patients with chronic kidney disease (CKD) or “uremic bleeding” is a well-recognized complication. It has been described as far back as 1907 by Reisman [(1)][1], classically as a complication of Bright disease.
Kevin R. Wheelan, Kevin R. Wheelan, Peter A. McCullough, Timothy Ball, Timothy Ball   +4 more
openaire   +3 more sources

No longer diseases of the wealthy : prevalence and health-seeking for self-reported chronic conditions among urban poor in Southern India [PDF]

, 2013
Background: The burden of chronic conditions is high in low-and middle-income countries and poses a significant challenge to already weak healthcare delivery systems in these countries. Studies investigating chronic conditions among the urban poor remain
Beerenahalli, Thriveni S, Bhojani, Upendra, Criel, Bart, Devadasan, Narayanan, Devadasan, Roopa, Kolsteren, Patrick, Munegowda, CM   +6 more
core   +2 more sources

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]

, 2019
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M, Bautista, Diana M, Brem, Rachel B, Brock, Emily C, Deguine, Jacques, Gronert, Karsten, Hill, Rose Z, Kucirek, Natalie, Rifi, Ziad, Schwendinger-Schreck, Jamie, Walsh, Carolyn M, Wei, Jessica   +11 more
core   +1 more source

Decrease in health-related quality of life associated with awareness of hepatitis C virus infection among people who inject drugs in Scotland [PDF]

, 2013
Chronic hepatitis C virus (HCV) infection can significantly reduce health-related quality of life (QoL), but it is not clear if reduction is associated with the infection or with being aware of one's infection status.
Allen, Elizabeth, Cameron, Sheila O., David J., Goldberg, Hutchinson, Sharon, McDonald, Scott, Palmateer, Norah Elizabeth, Taylor, Avril   +6 more
core   +1 more source

Prevalence of chronic kidney disease in the United States.

Journal of the American Medical Association (JAMA), 2007
CONTEXT The prevalence and incidence of kidney failure treated by dialysis and transplantation in the United States have increased from 1988 to 2004.
J. Coresh, E. Selvin, L. Stevens, J. Manzi, J. Kusek, P. Eggers, F. van Lente, A. Levey   +7 more
semanticscholar   +1 more source

Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts [PDF]

, 2014
BACKGROUND: This study aimed to assess associations of outdoor air pollution on prevalence of chronic bronchitis symptoms in adults in five cohort studies (Asthma-E3N, ECRHS, NSHD, SALIA, SAPALDIA) participating in the European Study of Cohorts for Air ...
Adam, M, Al-Kanaani, Z, Beelen, R, Birk, M, Brunekreef, B, Buschka, A, Cai, Y, Carsin, A, Cirach, M, Clavel-Chapelon, F, de Hoogh, K, de Nazelle, A, Declercq, C, Ducret-Stich, RE, Forsberg, B, Gerbase, MW, Hansell, AL, Hardy, R, Heinrich, J, Hoek, G, Jacquemin, B, Jarvis, D, Kauffmann, F, Keidel, D, Krämer, U, Kuh, D, Künzli, N, Marcon, A, Nieuwenhuijsen, MJ, Probst-Hensch, N, Ragettli, MS, Ranzi, A, Rochat, T, Sanchez, M, Schikowski, T, Schindler, C, Sugiri, D, Sunyer, J, Temam, S, Tsai, M, Valeria Ferretti, V, Varraso, R, Vierkötter, A   +42 more
core   +1 more source

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

Population Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKC subversion induces up-regulation of PKC II expression in B lymphocytes [PDF]

, 2015
Overwhelming evidence identifies the microenvironment as a critical factor in the development and progression of chronic lymphocytic leukemia, underlining the importance of developing suitable translational models to study the pathogenesis of the disease.
Cosimo, Emilio, Dunn, Karen, Gribben, John G., Holroyd, Ailsa, Mccaig, Alison M., McClanahan, Fabienne, Michie, Alison, Nakagawa, Rinako, Ramsay, Alan G., Tarafdar, Anuradha, Vukovic, Milica   +10 more
core   +3 more sources

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source