Results 61 to 70 of about 10,167,326 (383)

AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain [PDF]

open access: yes, 2017
Pain in sickle cell disease (SCD) is associated with increased morbidity, mortality, and high health care costs. Although episodic acute pain is the hallmark of this disorder, there is an increasing awareness that chronic pain is part of the pain ...
Aguilar   +89 more
core   +3 more sources

Kinematic Locomotion Changes in C57BL/6 Mice Infected with Toxoplasma Strain ME49

open access: yesMicroorganisms, 2019
Chronic infection with the intracellular parasite Toxoplasma gondii produces an accumulation of cysts in the brain and muscle, causing tissue damage. The cysts in the brain motor regions affect some kinematic locomotion parameters in the host.
María de la Luz Galván-Ramírez   +7 more
doaj   +1 more source

Chronic illness as biographical disruption.

open access: yesSociology of Health and Illness, 1982
The paper is based on semi-structured interviews with a series of rheumatoid arthritis patients. Chronic illness is conceptualised as a particular type of disruptive event.
M. Bury
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

From acute to chronic pain: tapentadol in the progressive stages of this disease entity [PDF]

open access: yes, 2017
OBJECTIVE: Chronic pain is now recognized as a neural disease, which results from a maladaptive functional and structural transformation process occurring over time. In its chronic phase, pain is not just a symptom but also a disease entity.
Coluzzi, Flaminia   +3 more
core  

Differences in Swedish and Australian medical student attitudes and beliefs about chronic pain, its management, and the way it is taught [PDF]

open access: yes, 2018
Background and aims: Medical students receive training in the management of chronic pain, but the training is often suboptimal. Considering that the basis for physician’s knowledge is their medical education, it is important to explore the attitudes and
Fowler, Christopher J   +3 more
core   +2 more sources

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

open access: yesNature Communications
Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands.
GBD 2019 Acute and Chronic Care Collaborators
doaj   +1 more source

Why Human Papillomavirus Acute Infections Matter

open access: yesViruses, 2017
Most infections by human papillomaviruses (HPVs) are `acute’, that is non-persistent. Yet, for HPVs, as for many other oncoviruses, there is a striking gap between our detailed understanding of chronic infections and our limited data on the early stages ...
Samuel Alizon   +2 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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