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Changes in Glutathione in Acute and Chronic Alcohol Intoxication

Pharmacology Biochemistry and Behavior, 1980
After 5 hours of acute ethanol intoxication, the levels of reduced glutathione of liver, heart, kidney and brain decreased to 60, 71, 70 and 83% of controls, respectively. The decrease was less when animals were pretreated with pyrazole. Pretreatment with disulfiram potentiated the effect of ethanol. Levels of GSSG were not altered by these treatments.
Consuelo Guerri, S Grisolia
exaly   +3 more sources

Some Biochemical Aspects of Chronic Alcohol Intoxication

Annals of Nutrition and Metabolism, 1977
Pathways of ethanol transformation and its respective metabolic disorders in the cell have been considered. One should note the role of acetaldehyde in the ethanol toxic effect. Acetaldehyde produces a significant effect upon the metabolism of biogenic amines in brain tissue.
exaly   +3 more sources

The Effect of Acute Alcohol Intoxication and Chronic Alcohol Abuse on Outcome From Trauma

open access: yesJAMA - Journal of the American Medical Association, 1993
To determine the effect of acute alcohol intoxication and chronic alcohol abuse on morbidity and mortality from trauma. —Prospective cohort study. —Blunt or penetrating trauma patients at least 18 years of age admitted to one trauma center or dying at ...
Richard Ries   +2 more
exaly   +2 more sources

Pathomorphological alterations in the kidneys in acute and chronic alcohol intoxication

Sudebno-meditsinskaya ekspertiza, 2022
The literature review presents data on pathomorphological changes in the kidneys in acute and chronic alcohol intoxication. A lack of consensus among researchers on the direct toxic damage to renal tissue by ethanol is demonstrated. Analysis of the literature showed that the issue of attributing microscopic changes detected in the kidneys to ...
A.V. Kovalev   +3 more
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ELECTROENCEPHALOGRAPHIC CHANGES ASSOCIATED WITH CHRONIC ALCOHOLIC INTOXICATION AND THE ALCOHOL ABSTINENCE SYNDROME

American Journal of Psychiatry, 1956
1. Correlative data on EEG changes, behavioral alterations and variations in blood alcohol level were obtained in 3 former narcotic addicts, without anamnestic, neurological or EEG evidence of central nervous system disorder, who received averages of 458-489 cc. of 95% ethyl alcohol daily for 48-55 days, followed by abrupt withdrawal of the drug, under
A, WIKLER   +3 more
openaire   +2 more sources

Alcohol intoxication and chronic alcoholism

2006
Abstract Alcoholism is drinking which results in impairment of physical and social health. Alcohol consumption contributes to 15-30% of male and 8-15% of female hospital admissions in the UK. Equivalent figures in the USA are slightly higher.
openaire   +1 more source

[Hormonal disorders in chronic alcoholic intoxication].

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985
Hormone levels were examined in the venous blood in 54 men suffering from stage 2 alcoholism and in 30 normal subjects, using a radioimmunochemical assay. The alcoholics were found to have a statistically significant increase in prolactin and a decrease in testosterone.
G P, Kolupaev, V A, Iakovlev
openaire   +1 more source

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