The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley +1 more source
Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation. [PDF]
Zhang C +6 more
europepmc +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
APPLICATION OF NANOCRYSTALS IN TREATMENT OF CHRONIC APICAL PERIODONTITIS
О.P. Kostyrenko +4 more
openaire +1 more source
A Non-Surgical Endodontic Treatment for a Dens in Dente Type II in a Maxillary Lateral Incisor with Chronic Apical Periodontitis: A Case Report. [PDF]
Zaatari WA, Tarakji M, Ayoubi HR.
europepmc +1 more source
Pharmacological activation of Nrf2 attenuated alveolar bone loss and protected periodontal tissues by reducing inflammation and oxidative stress, preserving collagen organization, and favoring bone homeostasis. Reversal of these effects by Nrf2 inhibition further supports Nrf2 signaling as a promising therapeutic target in periodontitis.
Vitória Bonan Costa +8 more
wiley +1 more source
Chronic apical periodontitis beyond infection: the impact of diet and lifestyle factors. [PDF]
Boca A +13 more
europepmc +1 more source
The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur +3 more
wiley +1 more source
[Endodontic retreatment of a maxillary second molar with chronic apical periodontitis and separated instrument: A case report]. [PDF]
Zang H, Liang Y.
europepmc +1 more source
Three‐Dimensional Scaffolds for Bone, Soft Tissue, and Periodontal Regeneration
Three‐dimensional scaffolds offer tissue‐specific control of architecture, mechanics, porosity, and functionalisation to improve bone, soft tissue, and periodontal regeneration. ABSTRACT The oral cavity presents three distinct regenerative challenges: restoration of alveolar bone volume and stability, augmentation of soft mucogingival tissues, and ...
Reuben Staples +5 more
wiley +1 more source

