Results 51 to 60 of about 2,135,829 (290)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Critical incidents of people with kidney transplants: discovered situations
This study aimed to identify the positive and negative situations experienced by people with kidney transplantations, using the Critical Incident Technique. A study with a descriptive-type qualitative approach, using the Critical Incidents Technique. The
Bianca Pozza dos Santos +4 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Background Individuals living with chronic conditions (CC) typically have a higher risk of more severe outcomes when exposed to infection. Although many studies have investigated the relationship between CCs and COVID-19 severity, they are generally ...
Nicholas Cheta +4 more
doaj +1 more source
Social disparities in the prevalence of multimorbidity – A register-based population study
Background Prevalences of multimorbidity vary between European studies and several methods and definitions are used. In this study we examine the prevalence of multimorbidity in relation to age, gender and educational attainment and the association ...
Michaela L. Schiøtz +4 more
doaj +1 more source
RECTAL CONDITIONS IN CHRONIC CONSTIPATION [PDF]
Prima facie, nothing appears easier than the diagnosis of chronic constipation. Nevertheless, in not a few cases, it may be an exceedingly difficult task to determine accurately the etiologic factor. Many cases are due to mechanical causes which, not infrequently, are never recognized or even suspected.
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
ENTEROCOLONIC CONDITIONS IN CHRONIC CONSTIPATION [PDF]
The fact that constipation has been and is under continuous discussion shows conclusively the lack of perfect knowledge emanating from any source. In this paper I shall include stasis and obstipation under the general term of constipation. No doubt there is an element of truth in the various explanations of constipation, but it may be safely asserted ...
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

