Results 141 to 150 of about 92,292 (242)

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Factors Associated With the Severity of Chronic Constipation Among Japanese University Students. [PDF]

JGH Open
Vu NTH, Lam HT, Miyauchi S, Ishiuchi N, Yoshino A, Miyake Y, Oka S, Okamoto Y, Quach DT, Tanaka S, Hiyama T.   +10 more
europepmc   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Chronic Constipation With a Rare Complication of Ischemic Stercoral Perforation of the Rectum: A Case Report. [PDF]

Cureus
ESayed OM, Almansouri FA, Zahid MM, Alshmaily HO, Alrmaly HF.   +4 more
europepmc   +1 more source

Association of Mediterranean Diet Adherence With Chronic Constipation and Chronic Diarrhea: Findings From NHANES. [PDF]

Food Sci Nutr
Xu C, Lin YH, Yu XC, Huang GB, Hu JY, Shen H, Li CC.   +6 more
europepmc   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Relationship between prescription medication use and chronic constipation and chronic diarrhea in US adults: A propensity score matching study

Precision Medical Sciences, EarlyView.
This study aimed to clarify the relationship between prescription medication use with chronic diarrhea (CD) and chronic constipation (CC) in adults. Population data was extracted from the 2007–2008 and 2009–2010 National Health and Nutritional Examination Surveys (NHANES). Multivariable logistic regression was used to calculate odds ratios (ORs) and 95%
Wei Wang, Jianan Ding, Xiaoyu Zhou, Yuanyuan Wen   +3 more
wiley   +1 more source

A comprehensive scoring system for defecation disorders derived by merging various validated patient-reported outcome measures for fecal incontinence, chronic constipation, and obstructed defecation. [PDF]

Int J Colorectal Dis
Ratto C, Simonelli I, Campennì P, Litta F, Pagano M, Parello A, Marra AA.   +6 more
europepmc   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

The "Fecal" breath: a case report of acute hypoxic respiratory failure from fecal aspiration with stercoral colitis in chronic constipation. [PDF]

Ann Med Surg (Lond)
Ingawale S, Ammar A, Kothari R, Karki S, Sharma P, Farhan M.   +5 more
europepmc   +1 more source