Results 161 to 170 of about 165,253 (350)
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth+10 more
wiley +1 more source
Abstract Objective Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and treatment involves nonpharmacological and pharmacological therapies, even if there is no optimal therapy. This randomized, placebo‐controlled, double‐blind trial aimed to evaluate the efficacy of calcium butyrate supplementation in ...
Fernanda Cristofori+11 more
wiley +1 more source
Psyllium is superior to docusate sodium for treatment of chronic constipation [PDF]
Mcrorie+5 more
openalex +1 more source
Genital Crohn's disease in pediatrics and genetic associations
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang+5 more
wiley +1 more source
The article discusses the study of cell metabolism condition in chronic constipation children based on the activities of the two mitochondrion enzymes, succinate dehydrogenate and glycerophosphate dehydrogenase detected in cytochemical analysis of blood ...
G.F. Semenova+5 more
doaj +2 more sources
Abstract Gastrointestinal (GI) bleeding can be a common symptom in the pediatric population. Vascular malformations, which cause symptoms based on their location and effect on surrounding structures, are an uncommon cause of GI bleeding. We present the case of a 6‐year‐old male with a 1‐year history of hematochezia, constipation, and microcytic anemia.
Kathleen Ordas+5 more
wiley +1 more source
Diagnostic dilemmas and results of treatment for chronic constipation. [PDF]
C.W. Keuzenkamp-Jansen+3 more
openalex +1 more source
Abstract Gastric heterotropia (GHT) may present from the oropharynx to the anus and is commonly associated with Meckel's diverticula. Here, we describe a rare case of anorectal GHT localized to the distal anal canal. A 14‐month‐old male patient presented for evaluation of rectal bleeding, severe constipation, and abdominal distention with poor response
Kathryn M. Stephenson+3 more
wiley +1 more source
Frequency of Digital Rectal Examination in Children With Chronic Constipation [PDF]
David Gold+4 more
openalex +1 more source
The Interplay between Hormones and Irritable Bowel Disease [PDF]
Thesis (M.A.)--Boston UniversityThis thesis examines the underlying mechanisms causing the severe and often debilitating symptoms associated with both Irritable Bowel Syndrome and Inflammatory Bowel Disease.
Linson, Elyse A.
core +1 more source