Chronic constipation is a common gastrointestinal disorder in older adults, and it is very important to manage chronic constipation. However, evaluating these subjective symptoms is extremely difficult in cases where patients are unable to express their ...
Masaru Matsumoto+12 more
doaj +1 more source
Research progress on the role of intestinal microbial imbalance in chronic constipation [PDF]
Chronic constipation is the prototype of functional constipation, and its morbidity increases gradually with aging. Intestinal microorganisms are involved in the occurrence, development, pathophysiology and other processes of chronic constipation.
YANG Jing-jing, CHEN Jia-yu
doaj
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
The pathophysiology of chronic constipation [PDF]
Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent stools, difficult stool passage or both. The common approach to the pathophysiology of constipation groups the disorder into primary and secondary causes. Primary causes are intrinsic problems of colonic or anorectal function, whereas secondary causes are ...
Christopher N. Andrews, Martin Storr
openaire +3 more sources
Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus
Aim. An appraisal of practitioners with chronic constipation management details in older and senile adults.Key points. Chronic constipation is a common issue in geriatrics.
V. T. Ivashkin+11 more
doaj +1 more source
Modeling chronic pain experiences from online reports using the Reddit Reports of Chronic Pain dataset [PDF]
Objective: Reveal and quantify qualities of reported experiences of chronic pain on social media, from multiple pathological backgrounds, by means of the novel Reddit Reports of Chronic Pain (RRCP) dataset, using Natural Language Processing techniques.
arxiv +1 more source
Are Concepts About Constipation and Dietary Fiber Changing?
After reading in detail the valuable review article by Korgh et al1 regarding chronic constipation management, we would like to mention some new points about chronic constipation which were not considered in this review.
Shahram Manoochehry, Hamid Reza Rasouli
doaj +1 more source
CHRONIC CONSTIPATION IS A RISK FACTOR FOR METABOLIC SYNDROME [PDF]
Background and aim: A recent epidemiologic survey in the U.S. provides indirect evidence that constipation is a risk factor for cardiovascular disease in postmenopausal females.
A. D'Alessandro+6 more
core +1 more source
Psyllium seed may be effective in the treatment of gastroesophageal reflux disease (GERD) in patients with functional constipation [PDF]
GERD, return of stomach contents into the esophagus, is one of the most common gastrointestinal disorders in medicine. Its common symptoms are heartburn and acid reflux.
Hosseini, Mousalreza+2 more
core +1 more source
Chronic constipation in children [PDF]
Difficulty in defecation, with or without soiling, is often encountered in children. It presents a management problem for general practitioners, and parental concern is often high. Constipation accounts for about 25% of a paediatric gastroenterologist's work and is one of the 10 most common problems seen by general paediatricians.1 We outline the ...
Greg Rubin, Anne Dale
openaire +3 more sources