Dietary strategies for chronic constipation: smartly targeting hormonal and reflex pathways for optimal recovery. [PDF]
Ribichini E +4 more
europepmc +1 more source
Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases
Abstract This case series explores the feasibility and clinical considerations of implementing the ketogenic diet therapy (KDT) for epilepsy management in patients with ileostomies. Two pediatric patients with medication‐resistant epilepsy and ileostomies continued KDT under clinical supervision.
Braden J. Baker +5 more
wiley +1 more source
Early Therapeutic Response Predicts Outcome in Chronic Constipation: A Multicenter Prospective Observational Study. [PDF]
Oshima T +9 more
europepmc +1 more source
Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation. [PDF]
Kalra S +5 more
europepmc +1 more source
Colonic transit study in patients with chronic constipation using Japanese-made radiopaque markers. [PDF]
Kamiya T +7 more
europepmc +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo- and positive-controlled thorough QT study [PDF]
Vandeplassche, L +13 more
core +1 more source
Core stability in women with and without chronic pelvic pain
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin +5 more
wiley +1 more source
The macrogol revolution in the treatment of chronic constipation. A short history of laxatives. [PDF]
Corazziari ES.
europepmc +1 more source
Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf +8 more
wiley +1 more source

