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Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation.
Gastroenterology, 2023BACKGROUND & AIMS Despite therapeutic advances, effective treatments for chronic constipation remain an unmet need. The vibrating capsule is a non-pharmacologic, orally-ingested, programmable capsule that vibrates intraluminally to induce bowel movements.
S. Rao +4 more
semanticscholar +1 more source
Food & Function, 2022
A variety of opinions exist on the potential of probiotics to provide relief from chronic constipation with much focus being placed on their mechanism of action and causes of heterogeneity in the results of different studies.
Luyao Wang +10 more
semanticscholar +1 more source
A variety of opinions exist on the potential of probiotics to provide relief from chronic constipation with much focus being placed on their mechanism of action and causes of heterogeneity in the results of different studies.
Luyao Wang +10 more
semanticscholar +1 more source
Atlanta journal-record of medicine
Chronic constipation is one of the most common health disorders in all of medicine. Its extent ranges from mild discomfort, which is usually easy to improve, to severe functional limitations that may significantly reduce quality of life and may be refractory to various treatment approaches. Our understanding of the pathomechanism has grown considerably
Viola, Andresen, Peter, Layer
+8 more sources
Chronic constipation is one of the most common health disorders in all of medicine. Its extent ranges from mild discomfort, which is usually easy to improve, to severe functional limitations that may significantly reduce quality of life and may be refractory to various treatment approaches. Our understanding of the pathomechanism has grown considerably
Viola, Andresen, Peter, Layer
+8 more sources
Impact of chronic constipation on health‐related quality of life and work productivity in Japan
Journal of Gastroenterology and Hepatology, 2020The impact of chronic constipation on health‐related quality of life (HRQoL), work productivity, and healthcare resource use in Japan is not well understood.
T. Tomita +5 more
semanticscholar +1 more source
American Journal of Gastroenterology, 2020
INTRODUCTION This is the first prospective, double-blinded, randomized, placebo-controlled trial to evaluate the safety and efficacy of a stimulant laxative compared with an osmotic agent for the treatment of chronic idiopathic constipation.
D. Morishita +6 more
semanticscholar +1 more source
INTRODUCTION This is the first prospective, double-blinded, randomized, placebo-controlled trial to evaluate the safety and efficacy of a stimulant laxative compared with an osmotic agent for the treatment of chronic idiopathic constipation.
D. Morishita +6 more
semanticscholar +1 more source
Alimentary Pharmacology and Therapeutics, 2020
Patients with chronic constipation (CC) or with irritable bowel syndrome with constipation are often dissatisfied about their medical therapy, but their condition remains poorly defined.
G. Basilisco
semanticscholar +1 more source
Patients with chronic constipation (CC) or with irritable bowel syndrome with constipation are often dissatisfied about their medical therapy, but their condition remains poorly defined.
G. Basilisco
semanticscholar +1 more source
2021
Chronic constipation is a common condition affecting quality of life. Three subtypes of primary constipation are generally recognized, although there is overlap among them: normal-transit constipation, rectal evacuation disorders, and slow-transit constipation. The first step in diagnosis is exclusion of alarm symptoms. The second step is a therapeutic
openaire +2 more sources
Chronic constipation is a common condition affecting quality of life. Three subtypes of primary constipation are generally recognized, although there is overlap among them: normal-transit constipation, rectal evacuation disorders, and slow-transit constipation. The first step in diagnosis is exclusion of alarm symptoms. The second step is a therapeutic
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Therapeutische Umschau. Revue therapeutique, 2007
Complaints of chronic constipation may substantially impair the quality of life of a patient. The disease feeling is shaped not only by objective parameters but also by subjective perceptions. This is along-considered into the so-called Rome-III-criteria. In the majority of the patients no distinct pathology can be found.
openaire +3 more sources
Complaints of chronic constipation may substantially impair the quality of life of a patient. The disease feeling is shaped not only by objective parameters but also by subjective perceptions. This is along-considered into the so-called Rome-III-criteria. In the majority of the patients no distinct pathology can be found.
openaire +3 more sources