Results 81 to 90 of about 114,727 (279)

Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of TSG-6

open access: yesFrontiers in Immunology
BackgroundInflammatory bowel disease (IBD), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to the limitations of current treatments, including drug resistance and invasive surgical
Bihua Wu   +6 more
doaj   +1 more source

Studies on the rejection of the transplanted homologous dog liver. [PDF]

open access: yes, 1961
Dogs in which livers have been replaced with hepatic homografts usually die in 5 to 10 days. Liver metabolism is not detectably abnormal at first, but gradual deterioration of function commences on the fourth or fifth day.
BROCK, DR   +3 more
core   +1 more source

Geometrically Templated, Ultra‐Lightweight and High Strength Soap Films from Lyotropic Liquid Crystalline Graphene Oxide/Polymer Composites

open access: yesAdvanced Functional Materials, EarlyView.
Shellular materials form spontaneously by dip coating the primitive triply periodic minimal surface (TPMS) wireframe in an aqueous solution of lyotropic liquid crystalline graphene oxide (GO) nanosheets mixed with polymers. Regulated by surface tension, GO nanosheets align on the polymer soap film as the stress builds up during drying.
Yinding Chi   +9 more
wiley   +1 more source

Disc disease: A summary and review [PDF]

open access: yes, 1993
A review of the etiology, clinical, radiological and laboratory presentation, differential diagnosis and management goals of disc disease is presented.
Walker, B.F.
core   +1 more source

Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophy [PDF]

open access: yes, 2008
The role of heterotopic (migratory) motoneurons (HMN) in the pathogenesis of spinal muscular atrophy (SMA) is still controversial. We examined the occurrence and amount of HMN in spinal cord tissue from eight children with SMA (six with SMA-I and two ...
Barišić, Nina   +10 more
core   +1 more source

A Self‐Curling Si3N4‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

open access: yesAdvanced Functional Materials, EarlyView.
Si3N4‐enhanced bioactive nanostructured adhesive wrap enables rapid conduit formation in wet environments, simplifying surgical procedures. Incorporated Si3N4 undergoes controlled hydrolysis within nanofibers, multi‐directionally modulating the peripheral nerve repair microenvironment for effective suture‐free repair.
Pengchao Ma   +10 more
wiley   +1 more source

Expert-level detection of acute intracranial hemorrhage on head computed tomography using deep learning. [PDF]

open access: yes, 2019
Computed tomography (CT) of the head is used worldwide to diagnose neurologic emergencies. However, expertise is required to interpret these scans, and even highly trained experts may miss subtle life-threatening findings. For head CT, a unique challenge
Hӓne, Christian   +4 more
core  

Buckling‐Resistant and Trace‐Stacked (BRATS) Design Enables Aid‐Free Implantation of Flexible Multielectrode Array with Minimized Inflammatory Tissue Response

open access: yesAdvanced Functional Materials, EarlyView.
Buckling‐resistant and trace‐stacked (BRATS) intracortical microelectrode arrays (MEAs) eliminate the need for insertion aid and complex surgical setup, resulting in minimal inflammatory tissue response, compared to conventional flexible MEAs inserted with aid. Trace stacking effectively doubled the channel count without increasing the MEA shank width,
May Yoon Pwint, Delin Shi, X. Tracy Cui
wiley   +1 more source

The pathogenesis of tendinopathy. A molecular perspective [PDF]

open access: yes, 2004
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

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