Results 61 to 70 of about 20,591 (212)

Associação entre lúpus eritematoso e tabagismo Association between lupus erythematosus and smoking

Anais Brasileiros de Dermatologia, 2008
FUNDAMENTOS: O lúpus eritematoso é doença crônica, auto-imune, que reúne manifestações exclusivamente cutâneas ou multissistêmicas, caracterizada pela produção de auto-anticorpos contra vários constituintes celulares.
Júnia Maria Fernandes Araújo, Ana Rosa Magaldi Ribeiro de Oliveira, Sâmya Diégues Cedrim, Olímpia Castelo Tristão, Aloísio Gamonal   +4 more
doaj   +1 more source

CHRONIC CUTANEOUS LUPUS ERYTHEMATOSUS (DLE)—

Medicine, 1976
Clinical and laboratory data are presented from a study of a group of 80 patients with chronic cutaneous discoid lupus erythematosus. These data support the contention that if one selects patients with chronic scarring DLE who have no evidence by history or physical examination of extracutaneous involvement, then only a small percentage of patients ...
S D, Prystowsky, J H, Herndon, J N, Gilliam   +2 more
openaire   +2 more sources

Impact of Co‐Morbid Immunocompromise in HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

The Laryngoscope, EarlyView.
Among patients with surgically resected Human Papillomavirus positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC), immunocompromised patients had significantly worse overall survival compared to the non‐compromised group; however, these exploratory findings should be interpreted cautiously.
Maxwell L. Weng, Tereza Vitkovska, Song Hon Hwang, Lauran K. Evans, Hong‐Ho Yang, Christopher Dann, Dipti Sajed, Maie A. St. John   +7 more
wiley   +1 more source

SkinDB: A Curated Resource for Dermatological Data Warehousing and Bioinformatics Exploration

Med Research, EarlyView.
SkinDB is an open‐access transcriptomic database integrating 220 datasets and 11,283 samples across six major skin diseases. Its code‐free interface supports cross‐disease analyses, visualizations, and data downloads for dermatological research. ABSTRACT Dermatology lacks a centralized analysis‐ready transcriptomic resource, leaving publicly available ...
Haoxue Zhang, Xiangnan Zhou, Hao Chi, Youping Deng, Lauren Higa, Isam Mohd Ibrahim, Xiaoyong Liu, Yuyao Liu, Jingyuan Ning   +8 more
wiley   +1 more source

Persistent lip enlargement: An unusual presentation of lupus erythematosus

International Journal of Women's Dermatology, 2017
Macrocheilia is a challenging problem with a variety of underlying causes that are both local and systemic, and granulomatous causes underlie the majority of cases.
A. Nikoo, M. Daneshpazhooh, S. Fahim, A. Ghanadan, H. Mahmoudi, L. Izadi Firoozabadi   +5 more
doaj   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Cutaneous manifestations of systemic lupus erythematosus and coexisting dermatologic conditions

Терапевтический архив
Aim. To analyze the clinical heterogeneity of cutaneous manifestations in systemic lupus erythematosus (SLE) and the features of coexisting dermatologic conditions in these patients. Materials and methods.
Anastasiia A. Shumilova, Ekaterina I. Travkina, Polina A. Sholkina, Tatiana M. Reshetnyak   +3 more
doaj   +1 more source

Genome-wide transcriptional profiling data from chronic cutaneous lupus erythematosus (CCLE) peripheral blood

Data in Brief, 2015
The disease Lupus erythematosus (LE), exhibits a variety of clinical manifestations with potentially wide-ranging multi-organ damage to joints, tendons, kidney, lung, heart, blood vessels, central nervous system and skin [1,2] Systemic changes are likely
R. Dey-Rao, A.A. Sinha
doaj   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

Rheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura, Yasuhiro Katsumata, Yuko Okamoto, Masayoshi Harigai   +3 more
wiley   +1 more source

Granzyme K: A new frontier in systemic lupus erythematosus

Rheumatology &Autoimmunity, EarlyView.
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen, Yunjing Pu, Peihui Yang, Qinghuan Zhu, Haojun Long, Danqi Deng   +5 more
wiley   +1 more source