Results 181 to 190 of about 100,035 (245)

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit   +7 more
wiley   +1 more source

Sustained relief of chronic headache using percutaneous 60-day peripheral nerve stimulation treatment: 12-month results from a multicenter, prospective clinical study. [PDF]

open access: yesInterv Pain Med
McCormick ZL   +10 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Transporter‐Mediated Drug–Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke   +8 more
wiley   +1 more source

“Efforts to Surface the Unspoken”: A Mixed Methods Study of a Risk‐Informed Check‐In in Norwegian Family Mediation

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT In family mediation, emotional discomfort and perceived unsafety may signal deeper relational risks, including postseparation violence. Standard intake procedures in Norwegian family mediation depend on disclosure to a nonclinical administrator before any therapeutic relationship exists, and research documents systematic under‐reporting at ...
Jan Stokkebekk   +2 more
wiley   +1 more source

Classroom boundaries and teacher agency: Challenges of implementing Ireland's new primary curriculum

open access: yesThe Curriculum Journal, EarlyView.
Abstract This article reports on a doctoral study examining teacher agency in one Irish primary school at a timely moment ahead of the implementation of the new Primary Curriculum Framework in September 2025. The framework embeds teacher agency as a central professional principle, yet findings from this study reveal a more cautious and bounded reality.
Máiréad Nally   +2 more
wiley   +1 more source

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