Results 51 to 60 of about 5,016,105 (350)
Quality assessment from biobank plasma and serum specimens: a systematic review [PDF]
PeerJAccurate assessment of serum and plasma quality is essential for reliable biobanking and research. This systematic review synthesizes 46 studies and shows that current evaluation methods prioritize sample processing delays, freeze-thaw cycles, storage ...
Xiongshun Liang +5 more
doaj +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Assessing chronic disease management in European health systems. Country reports [PDF]
, 2015 Many countries are exploring innovative approaches to redesign delivery systems to provide appropriate support to people with long-standing health problems.
Knai, C, Nolte, E
core
Comorbidities Associated with Large Abdominal Aortic Aneurysms [PDF]
, 2019 BACKGROUND: Abdominal aortic aneurysm has become increasingly important owing to demographic changes. Some other diseases, for example, cholecystolithiasis, chronic obstructive pulmonary disease, and hernias, seem to co-occur with abdominal aortic ...
Althoff, Christian E. +6 more
core +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
BMC Nephrology, 2021 Background We investigated whether implementation of the end-stage renal disease prospective payment system (ESRD PPS) was associated with changes in thrombolytic therapy use and other aspects of catheter management in hemodialysis (HD) patients. Methods
Nicholas S. Roetker +4 more
doaj +1 more source
Prevalence of disability according to multimorbidity and disease clustering: a population-based study [PDF]
, 2011 Background: The prevalence of chronic diseases has increased with population ageing, and research has attempted to elucidate the correlation between chronic diseases and disability. However, most studies in older populations have focused on the effect of
Angleman, Sara +2 more
core +1 more source
Craniopharyngioma – a chronic disease
Swiss Medical Weekly, 2018 As surgical expertise has a proven impact on post-treatment morbidity, medical societies should establish criteria of adequate professional expertise for surgical treatment of craniopharyngioma.
openaire +3 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Frontiers in Public Health, 2022 ObjectiveThis study aimed to perform a cluster analysis of symptoms linked with Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) and to identify which cluster of symptoms was associated with a higher risk of NG and CT.Study designFrom 15 April ...
Ning Ning +10 more
doaj +1 more source