Results 91 to 100 of about 5,896,146 (297)

Chronic wasting disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2007
Until recently, chronic wasting disease of cervids, the only prion disease affecting wildlife, was believed to be geographically concentrated to Colorado and Wyoming within the United States. However, increased surveillance has unveiled several additional pockets of CWD-infected deer and elk in 12 additional states and 2 Canadian provinces.
Sigurdson, C J, Aguzzi, A
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. [PDF]

, 2013
Recent data for the global burden of disease reflect major demographic and lifestyle changes, leading to a rise in non-communicable diseases. Most countries with high levels of tuberculosis face a large comorbidity burden from both non-communicable and ...
Abubakar, Ibrahim, Pletschette, Michel, Migliori, Giovanni Battistai, Migliori, Giovanni Battista, Zafar, Afia, Hoelscher, Michael, Pantaleo, Guiseppe, Kim, Peter, Lawn, Stephen D, Swaminathan, Soumya, Memish, Ziad A, Maeurer, Markus, Hasan, Rumina, Marais, Ben J., A Memish, Ziad, Marais, Ben J, Zumla, Alimuddin, Craig, Gill, Lawn, Stephen D., Glaziou, Philippe, Lönnroth, Knut, Mwaba, Peter, Schito, Marco, Zijenah, Lynn, Bates, Matthew, Memish, Ziad A., Colagiuri, Ruth, Mwaba, P., Zafar, A., Hasan, R., Zijenah, L., Marais, B.J., Glaziou, P., Kim, P., Abubakar, I., Pletschette, M., Lönnroth, K., Migliori, G.B., Hoelscher, M., Memish, Z.A., Bates, M., Craig, G., Lawn, S.D., Colagiuri, R., Pantaleo, G., Zumla, A., Schito, M., Maeurer, M., Swaminathan, S., Mwaba, P, Marais, BJ, Bates, M, Loennroth, K, Glaziou, P, Lawn, SD, Zijenah, L, Swaminathan, S, Colagiuri, R, Migliori, GB   +58 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Anaemia of chronic disease [PDF]

Clinical Medicine, 2013
#### Key points Anaemia of chronic disease is common and its diagnosis should prompt the search for an underlying systemic disorder if none is obvious It is important to exclude other causes of anaemia, especially iron deficiency Treatment of the underlying cause may improve anaemia, but ...
openaire   +2 more sources

Mechanisms by Which Interleukin-12 Corrects Defective NK Cell Anticryptococcal Activity in HIV-Infected Patients

mBio, 2016
Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important immune effector cells that directly recognize and kill C.
Stephen K. Kyei, Henry Ogbomo, ShuShun Li, Martina Timm-McCann, Richard F. Xiang, Shaunna M. Huston, Anutosh Ganguly, Pina Colarusso, M. John Gill, Christopher H. Mody   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Chronicle

, 2009
These editions of The Chronicle cover a range of topics related to chronic diseases. They include articles about local interventions and programs, research and data, policies, strategies, interstate initiatives, useful resources, upcoming events, and ...
Chronic Diseases Network
core   +1 more source

Chronic diseases and multi-morbidity - a conceptual modification to the WHO ICCC model for countries in health transition [PDF]

, 2014
BackgroundThe burden of non-communicable diseases is rising, particularly in low and middle-income countries undergoing rapid epidemiological transition.
Levitt, N.S., Nuala McGrath, Oni, T., McGrath, N., Rhonda BeLue, Tolu Oni, Naomi S Levitt, Oni, Tolu, Colagiuri, Stephen, May, C.R., May, Carl R, Roderick, P., Carl R May, Roderick, Paul, BeLue, R., BeLue, Rhonda, Stephen Colagiuri, Levitt, Naomi S, Colagiuri, S., McGrath, Nuala, Paul Roderick   +20 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source