Results 11 to 20 of about 304,162 (305)

Stimulation of zona incerta selectively modulates pain in humans

Scientific Reports, 2021
Stimulation of zona incerta in rodent models has been shown to modulate behavioral reactions to noxious stimuli. Sensory changes observed in Parkinsonian patients with subthalamic deep brain stimulation suggest that this effect is translatable to humans.
Charles W. Lu, Daniel E. Harper, Asra Askari, Matthew S. Willsey, Philip P. Vu, Andrew D. Schrepf, Steven E. Harte, Parag G. Patil   +7 more
doaj   +1 more source

Exercise challenge alters Default Mode Network dynamics in Gulf War Illness

BMC Neuroscience, 2019
Background Gulf War Illness (GWI) affects 30% of veterans from the 1991 Gulf War and has no known cause. Everyday symptoms include pain, fatigue, migraines, and dyscognition. A striking syndromic feature is post-exertional malaise (PEM).
Rakib U. Rayhan, Stuart D. Washington, Richard Garner, Kristina Zajur, Florencia Martinez Addiego, John W. VanMeter, James N. Baraniuk   +6 more
doaj   +1 more source

Perspective: Drawing on Findings From Critical Illness to Explain Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Frontiers in Medicine, 2022
We propose an initial explanation for how myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) could originate and perpetuate by drawing on findings from critical illness research.
Dominic Stanculescu, Jonas Bergquist, Jonas Bergquist   +2 more
doaj   +1 more source

Characterization of visual processing in temporomandibular disorders using functional magnetic resonance imaging

Brain and Behavior, 2023
Background and Purpose Many patients with chronic pain report hypersensitivity not only to noxious stimuli, but also to other modalities including innocuous touch, sound, and light, possibly due to differences in the processing of these stimuli. The goal
Daniel E. Harper, Kaundinya Gopinath, Jeremy L. Smith, Mia Gregory, Eric Ichesco, Sharon Aronovich, Richard E. Harris, Steven E. Harte, Daniel J. Clauw, Candace C. Fleischer   +9 more
doaj   +1 more source

Chronic fatigue syndrome

Nursing Management, 2020
Chronic fatigue syndrome (CFS) is characterized by severe fatigue and other non-specific symptoms. It causes disturbance of normal function. Uncertainty about etiology and the appropriate treatment, combined with high prevalence of psychiatric comorbidity, cause a problem in the perception of the disease by the patient, physician and society.This ...
John Nowicki, Michael T. Murray, Mark Dreher   +2 more
openaire   +7 more sources

Resting state connectivity correlates with drug and placebo response in fibromyalgia patients

NeuroImage: Clinical, 2014
Fibromyalgia is a chronic pain syndrome characterized by widespread pain, fatigue, and memory and mood disturbances. Despite advances in our understanding of the underlying pathophysiology, treatment is often challenging.
T. Schmidt-Wilcke, E. Ichesco, J.P. Hampson, A. Kairys, S. Peltier, S. Harte, D.J. Clauw, R.E. Harris   +7 more
doaj   +1 more source

“Pain, Stress, and Emotions”: Uncontrolled trial of a single-session, telehealth, emotional awareness and expression therapy class for patients with chronic pain

Frontiers in Pain Research, 2022
ObjectivesTrauma- and emotion-focused chronic pain interventions, particularly Emotional Awareness and Expression Therapy (EAET), show much promise for reducing pain and improving functioning.
Maisa S. Ziadni, John A. Sturgeon, Mark A. Lumley   +2 more
doaj   +1 more source

Fatigue in chronic cholestasis [PDF]

Gut, 2004
Fatigue is probably the most intriguing symptom affecting patients with chronic cholestatic disorders, in particular those with primary biliary cirrhosis. It is postulated that fatigue in patients with primary biliary cirrhosis may be associated with morphological abnormalities of the central nervous system secondary to accumulation of manganese ...
Piotr Milkiewicz, E.J. Heathcote
openaire   +3 more sources

Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study

NeuroImage: Clinical, 2018
Until recently, the predominant pathology of chronic pelvic pain conditions was thought to reside in the peripheral tissues. However, mounting evidence from neuroimaging studies suggests an important role of the central nervous system in the pathogenesis
Daniel E. Harper, Eric Ichesco, Andrew Schrepf, Megan Halvorson, Tudor Puiu, Daniel J. Clauw, Richard E. Harris, Steven E. Harte   +7 more
doaj   +1 more source

Amelioration of fatigue in chronic dialysis patients with dialysis solution employing electrolyzed water containing molecular hydrogen (H2) and its association with autonomic function balance

Renal Replacement Therapy, 2021
Background Enhanced oxidative stress is involved with fatigue in hemodialysis (HD) patients. Molecular hydrogen (H2) could improve the redox status. Thus, the study examines whether HD solution rendered by electrolyzed water containing H2 (E-HD) could ...
Yoshihiro Tsujimoto, Daisuke Kuratsune, Shigeru Kabayama, Mariko Miyazaki, Yasuyoshi Watanabe, Yoshiki Nishizawa, Masaaki Nakayama   +6 more
doaj   +1 more source