Results 91 to 100 of about 418,298 (339)

Cellular bioenergetics is impaired in patients with chronic fatigue syndrome

PLoS ONE, 2017
Chronic fatigue syndrome (CFS) is a highly debilitating disease of unknown aetiology. Abnormalities in bioenergetic function have been cited as one possible cause for CFS.
Cara Tomas, A. Brown, V. Strassheim, J. Elson, J. Newton, P. Manning   +5 more
semanticscholar   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

The relationship between chronic fatigue syndrome, burnout, job satisfaction, social support and age among academics at a tertiary institution

International Journal of Occupational Medicine and Environmental Health, 2019
Objectives Over the last 20 years, tertiary institutions have been subjected to several changes. This has resulted in increased workloads for academics.
Nicoleen Coetzee, David Jacobus Maree, Byron Nel Smit   +2 more
doaj   +1 more source

National Disability Insurance Scheme and Quality of Life Among Carers of Children With Autism Spectrum Disorder in Australia: A Thematic Analysis

Australian Journal of Social Issues, EarlyView.
ABSTRACT Diagnoses of autism spectrum disorder in Australia have increased considerably in recent years. The current study investigated how the National Disability Insurance Scheme (NDIS) impacts quality of life (QoL) among carers of children with autism spectrum disorder.
Jesse Gerhard, Sharon L. Grant
wiley   +1 more source

Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

Ibrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju, Samyuktha Villavan, Saranya Ravi, Roja Murugesan, Panneerselvam Theivendren, Vennila Jaganathan, Redlin Jani Rajan, Krupanidhi Karunanithi   +7 more
wiley   +1 more source

Chronic fatigue syndrome.

Nihon Naika Gakkai Zasshi, 1993
ごく最近,慢性疲労症候群, (chronic fatigue syndrome: CFS)が新しい疾患概念として社会的な話題となっている.著しい疲労感のため日常生活すら不能にしてしまうという症状を主徴としたこの疾患は欧米では早くから知られていたが,心因を基盤とした精神科領域の疾患とみなされていた. 1930年頃より集団発生がみられ,一層注目されることとなった.その後,各種の感染症の後にこの病態を示す例があることが知られ,特にウイルス感染に伴う器質的疾患という見方が次第に台頭してきた.しかし今までのところいくつかの病因候補ウイルスはあげられているものの,未だ病因は不明である.
openaire   +4 more sources

The Risk of Rheumatic Disorders Among Patients With Rhinosinusitis: A Systematic Review and Meta‐Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Emerging evidence suggests a possible link between rhinosinusitis and systemic rheumatic diseases; however, no meta‐analysis has comprehensively examined this association to date. We aimed to investigate if patients with rhinosinusitis have a predisposition to unmasking rheumatic diseases compared to individuals without ...
Arshbir Aulakh, Pradumn Choudhary, Gurwinder Sidhu, Deanna Gigliotti, Jane Jun, Andrew Thamboo   +5 more
wiley   +1 more source

Cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective. Re-analysis of a Cochrane review

Health Psychology Open, 2019
Analysis of the 2008 Cochrane review of cognitive behavioural therapy for chronic fatigue syndrome shows that seven patients with mild chronic fatigue syndrome need to be treated for one to report a small, short-lived subjective improvement of fatigue ...
Mark Vink, Alexandra Vink-Niese
doaj   +1 more source