The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger +1 more
wiley +1 more source
Sustained illness burden over time among Australians with myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]
Weigel B +3 more
europepmc +1 more source
Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu +17 more
wiley +1 more source
Gut Microbiome and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Insights into Disease Mechanisms. [PDF]
Nikolova R +3 more
europepmc +1 more source
Women's experiences of myalgic encephalomyelitis - chronic fatigue syndrome
C. Ingrid Deringer
openalex +1 more source
Is Chronic Fatigue Syndrome Synonymous with Effort Syndrome? [PDF]
S D Rosen +3 more
openalex +1 more source
A Review of NIDDK‐Funded Studies of Urological Chronic Pain Conditions
ABSTRACT Introduction This review highlights NIDDK‐funded clinical research studies focused on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Since 1987, the NIDDK has funded numerous cohort studies, epidemiologic studies, and clinical trials for these conditions.
J. Quentin Clemens
wiley +1 more source
The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. [PDF]
Rohrhofer J +4 more
europepmc +1 more source
P03.448 Neurasthenia-chronic fatigue syndrome. The basis and the meaning of medication and other therapy [PDF]
Luboš Janů, I. Prusa
openalex +1 more source
Physiological barriers to oral intake in survivors of critical illness: A scoping review
Abstract Oral nutrition is the predominant mode of nutrition delivery on the post–Intensive Care Unit (ICU) ward; yet, it is associated with lower intake than via enteral or parenteral nutrition. There are limited data on barriers that influence oral intake in ICU survivors.
Breanna J. Teleki +4 more
wiley +1 more source

