Results 221 to 230 of about 336,027 (339)

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

open access: yesMovement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger   +1 more
wiley   +1 more source

Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia

open access: yesMovement Disorders, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu   +17 more
wiley   +1 more source

Is Chronic Fatigue Syndrome Synonymous with Effort Syndrome? [PDF]

open access: bronze, 1990
S D Rosen   +3 more
openalex   +1 more source

A Review of NIDDK‐Funded Studies of Urological Chronic Pain Conditions

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction This review highlights NIDDK‐funded clinical research studies focused on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Since 1987, the NIDDK has funded numerous cohort studies, epidemiologic studies, and clinical trials for these conditions.
J. Quentin Clemens
wiley   +1 more source

The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. [PDF]

open access: yesDiagnostics (Basel)
Rohrhofer J   +4 more
europepmc   +1 more source

Physiological barriers to oral intake in survivors of critical illness: A scoping review

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Oral nutrition is the predominant mode of nutrition delivery on the post–Intensive Care Unit (ICU) ward; yet, it is associated with lower intake than via enteral or parenteral nutrition. There are limited data on barriers that influence oral intake in ICU survivors.
Breanna J. Teleki   +4 more
wiley   +1 more source

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