Results 31 to 40 of about 177,763 (250)
Moxibustion upregulates hippocampal progranulin expression
In China, moxibustion is reported to be useful and has few side effects for chronic fatigue syndrome, but its mechanisms are largely unknown. More recently, the focus has been on the wealth of information supporting stress as a factor in chronic fatigue ...
Tao Yi +6 more
doaj +1 more source
ごく最近,慢性疲労症候群, (chronic fatigue syndrome: CFS)が新しい疾患概念として社会的な話題となっている.著しい疲労感のため日常生活すら不能にしてしまうという症状を主徴としたこの疾患は欧米では早くから知られていたが,心因を基盤とした精神科領域の疾患とみなされていた. 1930年頃より集団発生がみられ,一層注目されることとなった.その後,各種の感染症の後にこの病態を示す例があることが知られ,特にウイルス感染に伴う器質的疾患という見方が次第に台頭してきた.しかし今までのところいくつかの病因候補ウイルスはあげられているものの,未だ病因は不明である.
openaire +3 more sources
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The syndrome of chronic fatigue is an extremely urgent and complex problem of modern medicine due to the widespread prevalence in the population, with a clear tendency to a steady increase in the incidence.
Nadezhda Bogdanovska +2 more
doaj +3 more sources
Ubiquity and formation of chronic fatigue in qualified sportsmen
Purpose: estimation of ubiquity of chronic fatigue among qualified sportsmen of Ukraine in different kinds of sports and determination of specificities of chronic fatigue syndrome’s formation among them.
V.N. Ilyin, A.R. Alwani
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Background. In modern medicine, chronic fatigue syndrome is an urgent problem for internists. The high prevalence of chronic fatigue syndrome, which has a significant impact on public health, requires primary care professionals to have an in-depth ...
L. A. Kamyshnikova, A. A. Zherdeva
doaj +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source

