Results 291 to 300 of about 2,642,809 (351)

Pediatric Brain Tumors in Western Kenya: Patient Outcomes and Healthcare Providers’ Perspectives

open access: yesPediatric Blood &Cancer, Volume 72, Issue 4, April 2025.
ABSTRACT Background Pediatric brain tumors are understudied compared to other pediatric malignancies in low‐ and middle‐income countries. Care delivery is inherently dependent on collaboration between multiple departments. This study aimed to present baseline data of pediatric neuro‐oncology care in Western Kenya and illustrate barriers and ...
Jesse Lemmen   +7 more
wiley   +1 more source

Efficacy and Safety of Dulaglutide Biosimilar LY05008 Versus the Reference Product Dulaglutide (Trulicity) in Chinese Adults With Type 2 Diabetes Mellitus: A Randomized, Open‐Label, Active Comparator Study

open access: yesJournal of Diabetes, Volume 17, Issue 4, April 2025.
ABSTRACT Background Dulaglutide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has been approved for improving glycemic control and reducing the risk of cardiovascular (CV) adverse events. A previous result in healthy Chinese male subjects demonstrated the pharmacokinetic (PK) similarity of LY05008 and the licensed product dulaglutide, with ...
Li Liu   +16 more
wiley   +1 more source

Meta‐Analysis: Inverse Association Between Helicobacter pylori Infection and Eosinophilic Oesophagitis

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 7, Page 1096-1109, April 2025.
In a large systematic review and meta‐analysis, exposure to Helicobacter pylori was significantly associated with decreased odds (46%) of eosinophilic oesophagitis and oesophageal eosinophilia. ABSTRACT Background Exposure to Helicobacter pylori (H. pylori) has been associated with a decreased risk of eosinophilic oesophagitis (EoE).
Irene Spinelli   +11 more
wiley   +1 more source

How I treat iron‐refractory iron deficiency anaemia—An expert opinion‐based treatment guidance for children and adults

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1067-1076, April 2025.
In iron‐refractory iron deficiency anaemia, inappropriately elevated hepcidin levels impair enteral iron absorption and iron release from macrophages by interacting with ferroportin. Oral iron supplements (containing ~30 mg Fe2+ per 100 mg) are generally ineffective due to this hepcidin–ferroportin interaction although, in some cases, this can be ...
V. Hoving   +3 more
wiley   +1 more source

Fixed dose combination of dapagliflozin, glimepiride and extended‐release metformin tablets in patients with type 2 diabetes poorly controlled by metformin and glimepiride: A phase III, open label, randomized clinical study in India

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 4, Page 2193-2205, April 2025.
Abstract Aim To evaluate the efficacy and safety of a triple fixed‐dose combination (FDC) therapy of dapagliflozin + glimepiride + metformin hydrochloride extended‐release (DAPA + GLIM + MET ER) tablets in Indian patients with type 2 diabetes mellitus (T2DM) inadequately controlled by combination of GLIM + MET.
Rakesh Sahay   +23 more
wiley   +1 more source

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