This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali +3 more
wiley +1 more source
Efficacy of metformin as an adjunct in periodontitis: A systematic analysis. [PDF]
Uddin MKH +7 more
europepmc +1 more source
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
Association of periodontitis with reduced kidney function and albuminuria in early chronic kidney disease: a population-based study. [PDF]
Schmidt-Lauber C +11 more
europepmc +1 more source
Irisin is an extracellular peptide stimulated by exercise and could act as both a biomarker and mediate the positive impact of exercise. This scoping review synthesizes human evidence on irisin variations in non‐communicable diseases, showing an increase of irisin in saliva and gingival tissues in periodontitis, potentially reflecting reparative or ...
Larysa Saboya Cavalotti Perdonsini +4 more
wiley +1 more source
Association of Gene Polymorphism of Matrix Metalloproteinase-9 With Chronic Periodontitis: A Cross-Sectional Survey in a South Indian Population. [PDF]
Mohamed SC +5 more
europepmc +1 more source
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister +6 more
wiley +1 more source
Comparative analysis of TNF-α, TLR-2, and TLR-4 in GCF before and after periodontal therapy. [PDF]
Terzi M, Altiparmak F, Yarkac FU.
europepmc +1 more source
Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias
Monocyte‐derived macrophages from successfully treated stage III periodontitis patients show a persistent skewing toward an M1‐like pro‐inflammatory phenotype across polarization conditions, suggesting that immune dysregulation may persist despite clinical periodontal stability.
Mariane Cristina Sloniak +5 more
wiley +1 more source
Comparative evaluation of open flap debridement with or without injectable platelet-rich fibrin in chronic periodontitis treatment. [PDF]
Verma S +6 more
europepmc +1 more source

