Results 91 to 100 of about 1,844,871 (401)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Prominent ‘Y’ descent is an ominous sign of a poorer prognosis in heart failure with preserved ejection fraction

ESC Heart Failure, 2019
Aims The heterogeneity of heart failure with preserved ejection fraction (HFpEF) represents different pathophysiological paths by which individual patients develop heart failure.
Daisuke Harada, Hidetsugu Asanoi, Takahisa Noto, Junya Takagawa   +3 more
doaj   +1 more source

2D Echocardiographic features in low T3 syndrome in chronic heart failure

Asian Journal of Medical Sciences, 2014
Background: Thyroid abnormalities are common in chronic heart failure. Severity of heart failure rises by several fold in patients with thyroid dysfunction.
Arun Kumar
doaj   +1 more source

Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure [PDF]

, 2006
Overactivation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) contributes to the development of cell dysfunction and tissue injury in various pathophysiological conditions associated with oxidative and nitrosative stress, including myocardial ...
Cziraki, A., Hasko, G., Liaudet, L., Mabley, J. G., Pacher, P., Szabo, C.   +5 more
core   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Predictors of chronic heart failure development and progression in pre-dialysis patients with chronic kidney disease

Počki, 2019
Background. Chronic kidney disease leads to early damage to the heart and blood vessels with the development of heart failure. The manifestation of one disease leads to the progression of another, since chronic heart failure is a condition in which the ...
V.V. Rodionova, O.O. Boyko, O.A. Turenko, O.O. Denisenko   +3 more
doaj   +1 more source

Impact of Frailty on Mortality and Hospitalization in Chronic Heart Failure: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Although frailty has been associated with increased risks for hospitalization and mortality in chronic heart failure, the precise average effect remains uncertain. We performed a systematic review and meta‐analysis to summarize the hazards for
Xiaobo Yang, J. Lupón, M. Vidán, C. Ferguson, P. Gastelurrutia, P. Newton, P. Macdonald, H. Bueno, A. Bayés‐Genís, J. Woo, E. Fung   +10 more
semanticscholar   +1 more source

Újdonságok a krónikus szívelégtelenség gyógyszeres terápiájában | Novelties in the pharmacological treatment of chronic heart failure [PDF]

, 2016
Absztrakt A krónikus szívelégtelenség gyógyszeres kezelését illetően számos új vizsgálat eredményét publikálták az elmúlt években, és 2016-ban megjelent az Európai Kardiológiai Társaság (ESC ...
Nyolczas, Noémi
core   +1 more source

Time Trends and Predictors of Gout Remission Over 6 Years

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Periodontitis in Chronic Heart Failure [PDF]

Texas Heart Institute Journal, 2016
Periodontal disease has been associated with an increased risk of cardiovascular events. The purpose of our study was to investigate whether a correlation between periodontitis and chronic heart failure exists, as well as the nature of the underlying cause.
Fröhlich, Hanna, Herrmann, Kristina, Franke, Jennifer, Karimi, Alamara, Täger, Tobias, Cebola, Rita, Katus, Hugo A, Zugck, Christian, Frankenstein, Lutz   +8 more
openaire   +4 more sources