Results 141 to 150 of about 1,844,871 (401)

Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy [PDF]

, 2014
Chronic neurohormonal and mechanical stresses are central fea-tures of heart disease. Increasing evidence supports a role forthe transient receptor potential canonical channels TRPC3 andTRPC6 in this pathophysiology.
Andersen, Asger, Birnbaumer, Lutz, Jo, Su-Hyun, Kass, David A., Lee, Dong-ik, Lepore, John J., Liu, Ting, Marino, Joseph P., Rainer, Peter P., Schnackenberg, Christine G., Seo, Kinya, Shalkey Hahn, Virginia, Willette, Robert N., Xu, Xiaoping   +13 more
core   +1 more source

Ultrasonic Atomization Spray Coating of PCL on an Mg‐Based Alloy Enhanced by Plasma Electrolytic Oxidation for Improved Adhesion, Corrosion Resistance, and Biocompatibility

Advanced Engineering Materials, EarlyView.
Plasma electrolytic oxidation is combined with ultrasonic spray deposition of polycaprolactone (PCL) on WE43 magnesium alloy to improve adhesion, corrosion resistance, and cytocompatibility. The hybrid coating demonstrates significantly reduced hydrogen evolution and enhances mechanical bonding, offering a promising strategy for next‐generation ...
Seyed Masih Mousavizadeh, Atiyeh Adelinia, Frederick D. Crowley, Jamal Seyyed Monfared Zanjani, John J. E. Mulvihill, Mingzhi Yu, Ehsan Rezvani, Matthijn de Rooij, Michael D. Gilchrist, Nan Zhang   +9 more
wiley   +1 more source

Chronic heart failure: actual aspects of treatment in real clinical practice

Медицинский совет, 2019
An urgent public health problem is the optimization of drug therapy in patients with chronic heart failure.A large number of works devoted to the treatment of chronic heart failure form the point of view that about the treatment of chronic heart failure «
D. I. Trukhan, E. L. Davydov
doaj   +1 more source

THE FUNCTION OF THE KIDNEYS IN PATIENTS SUFFERING FROM CHRONIC CARDIAC DISEASE WITHOUT SIGNS OF HEART FAILURE [PDF]

, 1928
Harold J. Stewart, John F. McIntosh
openalex   +1 more source

Rationale for current drug treatment [PDF]

, 2017
In the initial phase of heart failure, cardiac output and pressure are maintained by increasing sympathetic drive and by cell hypertrophy. Elevated end-diastolic volume, a reduced ejection fraction and a higher filling pressure also occur.
Burkart, F.
core  

Influence of Layering and Curie Temperature Uncertainty on the Performance of Multilayer Active Magnetic Regenerators

Advanced Functional Materials, EarlyView.
This study examines how manufacturing uncertainties in Curie temperatures (1.5–2°C) affect multilayer active magnetic regenerators (AMR). While increasing the number of magnetocaloric layers boosts cooling power, performance degrades due to temperature variations.
Urban Tomc, Guilherme F. Peixer, Christian R. H. Bahl, Kaspar K. Nielsen, Jaime A. Lozano, Jader R. Barbosa, A. Kitanovski   +6 more
wiley   +1 more source

Longitudinal multi-omics analysis uncovers the altered landscape of gut microbiota and plasma metabolome in response to high altitude

Microbiome
Background Gut microbiota is significantly influenced by altitude. However, the dynamics of gut microbiota in relation to altitude remains undisclosed.
Yang Han, Xiaoshuang Liu, Qian Jia, Jiayu Xu, Jinlong Shi, Xiang Li, Guotong Xie, Xiaojing Zhao, Kunlun He   +8 more
doaj   +1 more source

CLINICAL STUDIES OF THE BLOOD VOLUME. III. CHANGES IN BLOOD VOLUME, VENOUS PRESSURE AND BLOOD VELOCITY RATE IN CHRONIC CONGESTIVE HEART FAILURE [PDF]

, 1937
John G. Gibson, William A. Evans
openalex   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Anemia from the perspective of the problem of chronic heart failure: pathogenesis and laboratory diagnosis

Acta Medica Leopoliensia, 2018
Analyzing the data of the contemporary world literature, this paper presents the main points regarding etiological factors and pathogenesis of the contraction of anemia in patients with chronic heart failure.
V.P. Ivanov, M.O. Kolesnyk, O.M. Kolesnyk, Ye.I. Ivanova   +3 more
doaj   +1 more source