Results 71 to 80 of about 1,218,074 (349)
Time trends and predictors of gout remission over six years
Arthritis Care &Research, Accepted Article.Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah +5 more
wiley +1 more source
ESC Heart Failure, 2019 Aims The heterogeneity of heart failure with preserved ejection fraction (HFpEF) represents different pathophysiological paths by which individual patients develop heart failure.
Daisuke Harada +3 more
doaj +1 more source
Management of hyperkalaemia in acute kidney injury in a heart failure patient with patiromer
ESC Heart Failure, 2020 Aims One prevalent comorbidity of chronic heart failure (CHF) is chronic kidney disease(CKD). Hyperkalemia is associated with both CHF and CKD, which often leads to withdrawal of heart failure medications in clinical praxis. Methods and results A patient
Jonathan Slawik +3 more
doaj +1 more source
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018 Background Although frailty has been associated with increased risks for hospitalization and mortality in chronic heart failure, the precise average effect remains uncertain. We performed a systematic review and meta‐analysis to summarize the hazards for
Xiaobo Yang +10 more
semanticscholar +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Počki, 2019 Background. Chronic kidney disease leads to early damage to the heart and blood vessels with the development of heart failure. The manifestation of one disease leads to the progression of another, since chronic heart failure is a condition in which the ...
V.V. Rodionova +3 more
doaj +1 more source
What causes sudden death in patients with chronic heart failure and a reduced ejection fraction?
European Heart Journal, 2019 Sudden death characterizes the mode of demise in 30–50% of patients with chronic heart failure and a reduced ejection fraction. Occasionally, these events have an identifiable pathophysiological trigger, e.g.
M. Packer
semanticscholar +1 more source
Advanced Biology, EarlyView.Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang +6 more
wiley +1 more source
Chronic heart failure in adults: diagnosis and management
The Prescriber, 2019 NICE published a new guideline in September 2018 on the diagnosis and management of chronic heart failure in adults (NG106). This article provides a summary of the guideline and how it differs from previous NICE guidance and the 2016 SIGN guidance.
S. Chaplin
semanticscholar +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source