Results 131 to 140 of about 259 (175)

The Burden of Urticaria in the Middle East and North Africa Region From 1990 to 2021: A Systematic Analysis Based on the GBD Study 2021

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Urticaria is a condition which can impair the quality of life of affected individuals. There is a lack of recent studies on the burden of this disease in the Middle East and North Africa (MENA) region. This article reported the incidence, prevalence, and disability‐adjusted life years (DALYs) of urticaria from 1990 to 2021 ...
Amir Sajad Bagheryan   +6 more
wiley   +1 more source

Rupatadine Ameliorates Cisplatin‐Induced Hepatotoxicity in Rats: Targeting HMGB1/TLR4/NF‐κB and NLRP3/Caspase‐1 Signaling Pathways

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Graphical representation of the probable mechanisms underlying the effect of RUPA on CISP‐evoked hepatotoxicity in rats. ABSTRACT Despite cisplatin (CISP) is broadly employed in cancer therapy, its adverse effects, involving hepatotoxicity, restrict its clinical usage.
Shaimaa Mohamed Abdelrahman   +2 more
wiley   +1 more source

Patient Journey, Treatment Patterns, and Disease Burden of Patients With Idiopathic Hypereosinophilic Syndrome

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Idiopathic hypereosinophilic syndrome (I‐HES) is a rare disorder characterized by persistent eosinophilia without an identifiable underlying cause, leading to organ damage and dysfunction. The objectives of this study were to describe the real‐world demographics, patient journey, treatment patterns, and disease burden of patients ...
Juliana Schwaab   +9 more
wiley   +1 more source

Identification of Clinical Factors Associated With the Immunogenicity of Homologous ChAdOx1‐nCoV‐19 Vaccine in Hemodialysis Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT Hemodialysis (HD) patients are at higher risk of severe COVID‐19 and may exhibit suboptimal vaccine responses. This study evaluates the factors influencing vaccine‐induced immunity in HD patients following the second dose of the Vaxzevria. A total of 276 HD patients and 126 controls were included. Antibody responses were assessed using binding
Chia‐Wei Chang   +9 more
wiley   +1 more source

Bee Bread Protects Small Intestinal Mucosa and Modulates Local Redox Responses in Streptozotocin‐Induced Diabetic Rats

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 16, 27 August 2026.
In streptozotocin‐induced diabetic rats, bee bread supplementation attenuated diabetes‐associated intestinal mucosal alterations and modulated local redox responses. Treatment reduced blood glucose levels and influenced the immunoreactivity patterns of Mn‐SOD and CAT, supporting a protective role of bee bread in maintaining small intestinal mucosal ...
Ebru Karadag Sari   +4 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Unmet Needs in Treatment Escalation for Chronic Spontaneous Urticaria: Findings From the CURE Registry

open access: yesAllergy, Volume 81, Issue 8, Page 2804-2814, August 2026.
Appropriate treatment escalation improves CSU disease control. However, only about a quarter of patients achieve a complete response, the main goal of CSU treatment. Approximately one‐third of patients clinically eligible for escalation (UCT < 12) do not receive guideline‐recommended treatment escalation and remain symptomatic on their current ...
Pavel Kolkhir   +25 more
wiley   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, Volume 81, Issue 8, Page 2744-2774, August 2026.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier   +221 more
wiley   +1 more source

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