Results 101 to 110 of about 2,456,607 (422)

Cell Cycle Dysregulation and Renal Fibrosis

Frontiers in Cell and Developmental Biology, 2021
Precise regulation of cell cycle is essential for tissue homeostasis and development, while cell cycle dysregulation is associated with many human diseases including renal fibrosis, a common process of various chronic kidney diseases progressing to end ...
Yun-Shan Wu, Shan Liang, Dong-Yi Li, Jun-Hao Wen, Ji-Xin Tang, Ji-Xin Tang, Hua-Feng Liu   +6 more
doaj   +1 more source

Angiogenesis and chronic kidney disease [PDF]

Fibrogenesis & Tissue Repair, 2010
The number of patients requiring renal replacement therapy due to end-stage renal disease (ESRD) is increasing worldwide. The prevalence of chronic kidney disease (CKD), and the importance of CKD as a risk factor in development of ESRD and in complicating cardiovascular disease (CVD) have been confirmed. In recent years, the involvement of angiogenesis-
Hirofumi Makino, Yohei Maeshima
openaire   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

Clustering of Major Cardiovascular Risk Factors and the Association with Unhealthy Lifestyles in the Chinese Adult Population. [PDF]

PLoS ONE, 2013
Previous studies indicated that lifestyle-related cardiovascular risk factors tend to be clustered in certain individuals. However, population-based studies, especially from developing countries with substantial economic heterogeneity, are extremely ...
Bixia Gao, Luxia Zhang, Haiyan Wang, China National Survey of Chronic Kidney Disease Working Group   +3 more
doaj   +1 more source

Application of Direct Renin Inhibition to Chronic Kidney Disease [PDF]

, 2010
Chronic kidney disease has serious implications with a high risk for progressive loss of renal function, increased cardiovascular events as well as a substantial financial burden.
A Maione, A Ribeiro-Oliveira Jr, A Stanton, A Villamil, AS Go, B Pilz, BF Palmer, BH Oh, BM Brenner, C Ruster, CA Farquharson, CE Mogensen, Christian W. Mende, CM Ferrario, D Zeeuw de, DA Price, DH Endemann, DJ Kelly, DL Feldman, DP Ng, DW Wong, E Burgess, E Roig, EJ Lewis, EJ Lewis, F Laliberte, F Persson, F Persson, G Giacchetti, G Maschio, G Nguyen, H Kobori, HH Parving, HH Parving, HH Parving, J Coresh, J Nussberger, JF Mann, JJ McMurray, K Andersen, K Rossing, KJ Schjoedt, LF Fried, LJ Ellmers, M Azizi, M Azizi, M Azizi, M Burnier, M Epstein, M Mazzali, M Paul, M Ye, MA Pohl, MMWR, MR Weir, MR Weir, ND Fisher, NJ Brown, NK Hollenberg, NK Hollenberg, NK Hollenberg, P Ruggenenti, PA Sarafidis, R Dechend, RN Foley, S Anderson, S Bianchi, S Mezzano, S Oparil, SA Atlas, SA Yarows, SD Navaneethan, SG Chrysant, T Yamamoto, TH Jafar, U Wenzel, V Todorov, W Drummond, XR Huang, Y Huang, Y Uresin, YC Li   +81 more
core   +2 more sources

Chronic kidney disease in children [PDF]

Clinical Kidney Journal, 2016
Chronic kidney disease (CKD) is a major health problem worldwide. Although relatively uncommon in children, it can be a devastating illness with many long-term consequences. CKD presents unique features in childhood and may be considered, at least in part, as a stand-alone nosologic entity. Moreover, some typical features of paediatric CKD, such as the
BECHERUCCI, FRANCESCA, ROPERTO, ROSA MARIA, Materassi, Marco, ROMAGNANI, PAOLA   +3 more
openaire   +3 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Arteriolar hyalinosis and renal outcomes in patients with immunoglobulin A nephropathy

Renal Failure, 2022
Background The relationship between arteriolar hyalinosis and renal progression in immunoglobulin A nephropathy (IgAN) is not fully understood. We aimed to investigate the clinicopathological features and outcomes of IgAN with or without arteriolar ...
Yunzhu Shen, Tangli Xiao, ZhiKai Yu, Yinghui Huang, Ting He, Haiyang Li, Jun Zhang, Jiachuan Xiong, Jinghong Zhao   +8 more
doaj   +1 more source

Dataset Optimization for Chronic Disease Prediction with Bio-Inspired Feature Selection [PDF]

arXiv, 2023
In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The primary goal was to enhance the predictive accuracy of models streamline data dimensionality, and make predictions ...
arxiv