Results 101 to 110 of about 6,876,919 (290)

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP in chronic kidney disease (CKD) in primary care [PDF]

, 2009
Background: Chronic kidney disease (CKD) is a relatively newly recognised but common longterm condition affecting 5 to 10% of the population. Effective management of CKD, with emphasis on strict blood pressure (BP) control, reduces cardiovascular risk ...
Kevin Harris, Gallagher, Hugh, T. Chan (7638014), Kevin Harris (7638041), Hague, Nigel, Elizabeth du Bois, Jain, N, van Vlymen Jeremy, M. Nation (7638023), Iain Crinson, N. Thomas (7638017), van Vlymen, J, Chan Tom, van Vlymen, Jeremy, I. Crinson (7638032), Fiona Reid, Simon de Lusignan, Aumran Tahir, J. van Vlymen (7638020), Hugh Gallagher, de Lusignan Simon, de Lusignan, S, Nation Michael, S. de Lusignan (7638008), Gallagher Hugh, Tom Chan, Nigel Hague, Jain Neerja, Reid, Fiona, E. du Bois (7638029), Gallagher, H, du Bois Elizabeth, Thomas Nicki, A. Tahir (7638026), du Bois, E, Tahir Aumran, du Bois, Elizabeth, N. Jain (758322), Reid Fiona, Chan, Tom, Nation, Michael, Harris, Kevin, Crinson, Iain, Jeremy van Vlymen, Tahir, Aumran, Nation, M, Harris, K, Nicki Thomas, Reid, F, Chan, T, Crinson Iain, F. Reid (7638038), Hague, N, Neerja Jain, Crinson, I, Michael Nation, Hague Nigel, Jain, Neerja, Thomas, N, de Lusignan, Simon, Thomas, Nicki, H. Gallagher (7638011), Tahir, A, Harris Kevin, N. Hague (7638035)   +64 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Chronic kidney disease in the United States, 2019 [PDF]

With chronic kidney disease (CKD), kidneys become damaged over time or cannot clean the blood as well as healthy kidneys. When the kidneys don\u2019t work well, wastes and extra water build up in the body and may cause other health problems, including ...

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Examining the Relationship between “Neutrophil-to-Lymphocyte Ratio” and Peripheral Blood Inflammatory Factors in the Patients Undergoing Chronic Dialysis

Turkish Journal of Nephrology, 2023
Fariba Samadian , Nader Sigari , Sadra Ashrafi , Zhila Farzinpoor , Nooshin Dalili   +4 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease - prospective longitudinal study in a multiethnic population [PDF]

, 2014
Background: Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority populations.
Sutton, AJ, Kevin Harris, eGFR-C study group (7648493), Khunti, Kamlesh, Brettell, Elizabeth A., Stevens, PE, Sutton, Andrew J., Claire C Sharpe, Lamb, EJ, Brettell, Elizabeth A, Cockwell, P, F. Loud (7648475), Sutton, Andrew J, P. E. Stevens (7648484), Sharpe, Claire C, Sharpe, CC, J. J. Deeks (7648466), Edmund J Lamb, Maarten W Taal, A. J. Sitch (7642292), Deeks, Jon J., R. S. Ottridge (7648478), Kamlesh Khunti, Elizabeth A Brettell, Taal, Maarten W., Khunti, K, Ottridge, Ryan, Lamb, Edmund J., Brettell, EA, Sutton, Andrew, Sharpe, Claire C., Ryan S Ottridge, Ottridge, Ryan S, ?, ?, N. Dalton (7648463), P. A. Kalra (7648472), Dalton, N, Kalra, PA, Neil Dalton, Taal, Maarten W, Taal, MW, Philip A Kalra, Sharpe, Claire C; id_orcid, Loud, F, K. Harris (75473), Tracy Higgins, Andrew J Sutton, Deeks, Jon J, Loud, Fiona, Dalton, Neil, Higgins, Tracy, Ottridge, RS, Higgins, T, Sitch, Alice J, Deeks, JJ, Sitch, AJ, M. W. Taal (7648490), T. Higgins (7648469), A. J. Sutton (7648487), Harris, Kevin, Kalra, Philip A, Paul Cockwell, Sitch, Alice J., Paul E Stevens, Ottridge, Ryan S., Harris, K, Deeks, Jonathan, Jon J Deeks, Stevens, Paul E., Sitch, Alice; id_orcid, E. J. Lamb (7648454), Kamlesh Khunti (171607), Fiona Loud, Stevens, Paul E, Kalra, Philip A., Alice J Sitch, Cockwell, Paul, P. Cockwell (7648460), Lamb, Edmund J, C. C. Sharpe (7648481), E. A. Brettell (7648457)   +80 more
core   +3 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Projections of the prevalence of treated end-stage kidney disease in Australia 2012-2020 [PDF]

, 2014
This paper presents national level projections of the number of people receiving kidney replacement therapy for end-stage kidney disease for the period 2012 to 2020.

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