Results 281 to 290 of about 1,319,691 (347)

WCN25-520 International survey of nephrologists about referral of patient with advanced chronic kidney disease for kidney transplantation

Vivekanand Jha, Somaya Zahran, Shaifali Sandal, Elias Elenjickal, Marcelo Cantarovich, Maria Cristina Ribeiro de Castro, Gopal Basu, Mohammad Ghnaimat, Yewondwossen Tadesse, Jolanta Małyszko   +9 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Assessment of Bicarbonate Deficiency in Feline Acute and Chronic Kidney Disease. [PDF]

Vet Sci
Perondi F, Vernaccini M, Morelli S, Marchetti V, Lippi I.   +4 more
europepmc   +1 more source

CLINICAL UTILITY OF KIDNEY FAILURE RISK EQUATION IN DIABETES AND CHRONIC KIDNEY DISEASE

Ying Guat Ooi, Tharsini Sarvanandan, Nicholas Ken Yoong Hee, Quan Hziung Lim, Hooi Chin Beh, Nur Raziana Rozi, Christine Shamala Selvaraj, Adina Abdullah, Wan Ahmad Hafiz Wan Md Adnan, Sharmila S. Paramasivam, R. Jeyakantha Ratnasingam, Shireene Ratna Vethakkan, Pavai Sthaneswar, Soo Kun Lim, Lee‐Ling Lim   +14 more
openalex   +2 more sources

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Untargeted salivary metabolomics for pediatric chronic kidney disease diagnosis. [PDF]

Sci Rep
Unceta N, Sánchez-Ortega A, Gómez-Caballero A, Diez-Caballero L, Benito S, Gómez de Balugera Z, Szulimowska J, Zalewska A, Maciejczyk M, Taranta-Janusz K.   +9 more
europepmc   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

A retrospective cohort study on the bidirectional association between depression and chronic kidney disease. [PDF]

Front Nephrol
Jeun KJ, Brothers T, Shawwa K, Al-Mamun MA.   +3 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source