Results 191 to 200 of about 446,057 (263)

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report. [PDF]

Pharmacol Res Perspect
Uno T, Nakakura I, Ikeda A, Hosoda A, Mukai Y, Yamanishi K, Ohara N, Imanishi K, Une Y, Yokoyama S, Hosomi K.   +10 more
europepmc   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

The Association Between Pulmonary Hypertension, End-Stage Kidney Disease, and Death: An Analysis of the Chronic Renal Insufficiency Cohort Study (CRIC). [PDF]

Kidney Med
Tuttle M, Tighiouart H, Oka T, McCallum W, Navaneethan SD, Kawut SM, Sarnak MJ.   +6 more
europepmc   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Factors influencing perceived importance of haemodialysis adherence among end stage kidney failure patients in tertiary care centres in Nepal. [PDF]

PLoS One
Shrestha P, Koirala A, Satyal P, Bhurtel AM, Karmacharya BM.   +4 more
europepmc   +1 more source

Spironolactone or Finerenone for Cardiovascular and Kidney Protection in Patients with Moderate CKD? [PDF]

Am J Cardiovasc Drugs
Georgianos PI, Leptokaridou-Mourtzila E, Kourtidou C, Kontogiorgos I, Roumeliotis A, Vaios V, Liakopoulos V.   +6 more
europepmc   +1 more source

Clinical Significance of the C-Reactive Protein-Triglyceride-Glucose Index in Cardiovascular Disease, Stroke, Cardiovascular-Kidney-Metabolic Syndrome, Cancer, Diabetes, and Osteoporosis: A Narrative Review. [PDF]

Int J Gen Med
Yang S, Yao X, Chai J, Lu H, Tang W, Wu Z, He W, Xie Y.   +7 more
europepmc   +1 more source

Understanding by older patients of dialysis and conservative management for chronic kidney failure.

Am J Kidney Dis, 2015
Tonkin-Crine S, Okamoto I, Leydon GM, Murtagh FE, Farrington K, Caskey F, Rayner H, Roderick P.   +7 more
europepmc   +1 more source