Results 231 to 240 of about 272,468 (312)

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

Advanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan, Keying Xu, Yue Gao, Sheng Huang, Xueqian Xia, Xiang Liu, Shuangxue Pan, Chunpeng Jiao, Weijian Cheng, Yong Guo, Jingwen Zhao, Jia‐Wei Shen   +11 more
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Erratum: Acute kidney injury and acute-on-chronic liver failure classifications in prognosis assessment of patients with acute decompensation of cirrhosis [PDF]

, 2016

openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Clinical trial with traditional Chinese medicine intervention ''tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'' for chronic hepatitis B-associated liver failure

, 2014
Hanmin Li, Zhihua Ye, Jun Zhang, Xiang Gao, Yanming Chen, Xin Yao, Jian-Xun Gu, Lei Zhan, Yang Ji, Jianliang Xu, Ying-He Zeng, Fan Yang, Xiao Lin, Sheng Guo-guang, Xin Wei, Qi Long, Qingjing Zhu, Zhaohong Shi, Lianguo Ruan, Jiayao Yang, Changchun Li, Hongbin Wu, Shengduo Chen, Xin-La Luo   +23 more
openalex   +1 more source

Electrolyte and Acid-Base Disorders in Chronic Kidney Disease and End-Stage Kidney Failure [PDF]

, 2017
Tsering Dhondup, Qi Qian
openalex   +1 more source

Chinese Expert Consensus on Standardized Outpatient Management of Sarcopenia in the Elderly (2024)

AGING MEDICINE, EarlyView.
In China, specific sarcopenia clinics are not sufficient for outpatients. This consensus combines the professional advice of domestic geriatrics experts, summarizes the existing domestic experience in the establishment of sarcopenia clinics, and provides guidance for the management of sarcopenia clinics.
Zhang Qin, Kang Lin, Wang Jianye, Xi Huan, Yu Pulin, Zhang Cuntai, Hidenori Arai, Tuo Xiping, Yang Yunmei, Liu Xiaohong, Chen Chan, Chen Huaihong, Chen Xujiao, Cheng Lijuan, Deng Linzi, Ding Yi, Dong Birong, Dong Juan, Gao Yue, Gu Haifeng, Guo Yan, Han Hui, Hidenori Arai, Hu Fang, Shangcheng District, Hu Jian, Hu Yao‐min, Hu Yixin, Huang Gairong, Jian Zaijin, Jiang Wenjing, Kang Lin, Li Fuchao, Li Jian, Li Jing, Li Tianlang, Lin Fan, Liu Juan, Liu Xiaohong, Liu Xuejun, Lou Huiling, Luo Lan, Luo Man, Ma Lina, Mao Yongjun, Nie Jing, Ouyang Xiaojun, Qi Guoxian, Qiao Wei, Shi Hong, Tian Tao, Tuo Xiping, Wang Chaohui, Wang Jiaqiu, Wang Jianye, Wang Peng, Wang Quan, Wang Xiaonan, Wang Yuan, Wang Zhaodi, Wei Yanan, Wu Jun, Wu Shuhua, Wu Xiaohe, Xi Huan, Xin Xiaofeng, Xu Meiqun, Yang Yunmei, Yin Shi, Yu Plin, Zhang Cuntai, Zhang Qin, Zhang Xiaoyan, Zhang Ying, Zhao Xiaohong, Zhong Yuan, Zhou Baiyu, Zhou Houguang, Zhou Xiaohui   +78 more
wiley   +1 more source

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

AGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang, Yu‐Qing Ni, You‐Shuo Liu   +2 more
wiley   +1 more source

Exploring Potentially Inappropriate Medication Use on Elderly Patients in a General Medicine Ward Using 2023 AGS Beers Criteria

AGING MEDICINE, EarlyView.
This study found that 54% of elderly inpatients were prescribed at least one potentially inappropriate medication (PIM) based on the 2023 AGS Beers Criteria. Among identified PIMs, 32.2% were medications to avoid, and 52.8% required cautious use. Polypharmacy and chronic kidney disease (CKD) were key predictors of PIM use.
Subash Karki, Rahi Bikram Thapa, Rajeev Shrestha   +2 more
wiley   +1 more source

Interplay of parathyroid hormone and aldosterone antagonist in prevention of heart failure hospitalizations in chronic kidney disease

, 2014
Mona Hassan, Waqas Qureshi, Laila S Sroujieh, Derar Albashaireh, Sara BouMalham, Meghan G. Liroff, Waseem Amjad, Fatimah Khalid, Hiba Hadid, Zaid Alirhayim   +9 more
openalex   +1 more source