Results 241 to 250 of about 424,534 (311)

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang   +12 more
wiley   +1 more source

The impact of defunctioning ileostomies on postoperative kidney function in rectal cancer surgery. [PDF]

open access: yesColorectal Dis
Sandén G   +6 more
europepmc   +1 more source

Etiology of Chronic Renal Failure in Hodeida, Yemen. [PDF]

open access: yesKidney Int Rep
Al-Madwahi NY   +3 more
europepmc   +1 more source

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