Results 31 to 40 of about 690,557 (312)

Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcγ-Receptor Signaling Pathways

Frontiers in Immunology, 2021
The expression of Triggering Receptor Expressed on Myeloid cells (TREM)-1 has been described as a predictive marker for anti-Tumor Necrosis Factor (TNF)-α monoclonal antibody (mAb) therapy responsiveness in patients with inflammatory bowel disease (IBD).
Marileen M. Prins, Bram Verstockt, Bram Verstockt, Marc Ferrante, Marc Ferrante, Séverine Vermeire, Séverine Vermeire, Manon E. Wildenberg, Manon E. Wildenberg, Pim J. Koelink   +9 more
doaj   +1 more source

Chemerin in Liver Diseases [PDF]

, 2014
Chemerin is a chemoattractant protein and moreover has a role in adipogenesis, angiogenesis and glucose homeostasis. Chemerin is primarily synthesized and secreted by adipocytes and hepatocytes.
Buechler, Christa
core   +1 more source

Interferon signalling in the liver : implications for the natural course and therapy of hepatitis C [PDF]

, 2012
Hepatitis C virus is a global health concern, estimated to infect 2-3% of the world's population. Inter-individual differences in the course of infection and response to therapy, highlighted by recent genomewide association studies, point to the crucial ...
Makowska, Zuzanna
core   +1 more source

Nutrition and Chronic Liver Disease [PDF]

Canadian Journal of Gastroenterology and Hepatology, 1998
Malnutrition frequently occurs in patients with chronic liver disease, and may influence both short and long term clinical outcome in these patients. Therefore, nutritional intervention may play an important role in the management of chronic liver disease patients.
Wichai Siriboonkoom, Leah Gramlich
openaire   +3 more sources

Intracellular IL-24 ameliorates lipid metabolic disorders in metabolic dysfunction-associated steatohepatitis by restoring the autophagy-lysosome pathway

Cellular and Molecular Life Sciences
Background Metabolic dysfunction-associated steatohepatitis (MASH) is associated with impaired hepatic autophagy, but its key regulators remain unclear. This study delineates IL-24 as a regulator of autophagy in MASH.
Jiawei Cui, Zhandong Lin, Mengjiao Sun, Yuyuan He, Yaoyao Mao, Congyue Zhang, Yue Shi, Yukai Chen, Shaoya Li, Ying Zhang, Qianqian Zheng, Yuemin Nan   +11 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Serum microRNA-122 predicts survival in patients with liver cirrhosis

, 2012
Background: Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs) circulating in the blood are an emerging new class of biomarkers.
Stefan Zeuzem, Albrecht Piiper (22854), Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Verena Köberle (130993), Bernd Kronenberger (131004), Bernd Kronenberger, Verena Köberle, Waidmann, Oliver, Albrecht Piiper, Oliver Waidmann (130988), Piiper, Albrecht, Friederike Brunner (130998), Köberle, Verena, Brunner, Friederike, Zeuzem, Stefan, Stefan Zeuzem (22856)   +17 more
core   +1 more source

Decreased S100B expression in chronic liver diseases [PDF]

, 2018
Background/Aims: Hepatic innervation in liver diseases is not fully understood. We here evaluated S100B expression as a marker of hepatic nerves in patients with various chronic liver diseases, topographically and semi-quantitatively.
문일환, 유권, 김태헌
core   +2 more sources

Oral betaine ameliorates high-fat diet-induced hepatic steatosis in mice by inducing miR-96-5p targeting IGF1R

Journal of Functional Foods
Metabolic dysfunction–associated steatotic liver disease (MASLD) is a growing health concern with limited treatment options. Here we show that oral betaine attenuates high-fat diet (HFD)–induced steatosis in mice and oleic acid–induced lipid accumulation
Yuyao Xie, Ning Ding, Jing Sun, Xiuli Jin, Xinhe Zhang, Ji Sun, Hongli Xu, Hao Bing, Lin Guan, Yiling Li, Ningning Wang   +10 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source