Results 61 to 70 of about 4,104,552 (244)

Impact of gut microbiota on nonalcoholic fatty liver disease: insights from a leave-one-out cross-validation study

open access: yesFrontiers in Microbiology
IntroductionEnteric dysbacteriosis is strongly associated with nonalcoholic fatty liver disease (NAFLD). However, the underlying causal relationship remains unknown. Thus, the present study aimed to investigate the relationship between gut microbiota and
Tongtong Pan   +4 more
doaj   +1 more source

The Chronicle

open access: yes, 2003
These editions of The Chronicle cover a range of topics related to chronic diseases. They include articles about local interventions and programs, research and data, policies, strategies, interstate initiatives, useful resources, upcoming events, and ...
Chronic Diseases Network
core   +1 more source

An appraisal of the histopathological assessment of liver fibrosis [PDF]

open access: yes, 2006
One of the most important aspects of the histopathological assessment of liver biopsies in the setting of chronic liver disease is determination of the degree of fibrosis and architectural change.
Dhillon, A.P.   +4 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Chronicle

open access: yes, 2005
These editions of The Chronicle cover a range of topics related to chronic diseases. They include articles about local interventions and programs, research and data, policies, strategies, interstate initiatives, useful resources, upcoming events, and ...
Chronic Diseases Network
core   +1 more source

Ultrasound in chronic liver disease [PDF]

open access: yesInsights into Imaging, 2014
With the high prevalence of diffuse liver disease there is a strong clinical need for noninvasive detection and grading of fibrosis and steatosis as well as detection of complications.B-mode ultrasound supplemented by portal system Doppler and contrast-enhanced ultrasound are the principal techniques in the assessment of liver parenchyma and portal ...
Gerstenmaier, JF, Gibson, RN
openaire   +3 more sources

Association of early age at establishment of chronic hepatitis B infection with persistent viral replication, liver cirrhosis and hepatocellular carcinoma: a systematic review. [PDF]

open access: yes, 2013
Age at infection with hepatitis B virus (HBV) is a known risk factor for chronic HBV infection. However, in addition, there is some evidence that early age at infection further increases the risk of primary liver cancer beyond its association with ...
Bottomley, Christian   +21 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Cystic fibrosis related chronic liver disease: a study of its influence upon prognosis and possible mechanisms for this; with specific reference to pulmonary and systemic haemodynamics [PDF]

open access: yes, 1995
MDTo assess the influence of chronic liver disease on survival a time dependent multivariate Cox regression analysis was It performed. The results confirmed that patients with evidence of chronic liver disease have a worse prognosis.
Williams, Simon Graham John
core   +4 more sources

Dysfunctional macrophages along the gut-liver axis: a driver of infection in cirrhosis

open access: yesFrontiers in Immunology
Patients with cirrhosis are highly susceptible to infections which could trigger a vicious cycle of events, including hepatic decompensation, organ failure, and increased mortality.
Devrim Aslan   +11 more
doaj   +1 more source

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