Results 1 to 10 of about 24,300 (246)

Antithymocyte globulin therapy in chronic lung allograft dysfunction. [PDF]

Front Transplant
IntroductionLung transplantation has seen strides in survival over the past few decades, though long-term survival remains poor. Chronic lung allograft dysfunction (CLAD) is a leading cause of graft failure and mortality beyond the first year. Anti-thymocyte globulin (ATG) is commonly used for treating refractory CLAD, though its efficacy remains ...
Padhye AA, Guffey D, Leon-Pena A, Segraves J, Fernandez R, Loor G, Garcha P, Wu TD, Li G.   +8 more
europepmc   +6 more sources

Lung Transplantation: CT Assessment of Chronic Lung Allograft Dysfunction (CLAD) [PDF]

Diagnostics, 2021
Chronic lung allograft rejection remains one of the major causes of morbi-mortality after lung transplantation. The term Chronic Lung Allograft Dysfunction (CLAD) has been proposed to describe the different processes that lead to a significant and persistent deterioration in lung function without identifiable causes. The two main phenotypes of CLAD are
Anne‐Laure Brun, Marie-Laure Chabi, C. Picard, François Mellot, Philippe Greniér   +4 more
doaj   +6 more sources

Everolimus Treatment for Chronic Lung Allograft Dysfunction in Lung Transplantation. [PDF]

Life (Basel)
Our study aims to evaluate the effect of everolimus treatment on lung function in lung transplant (LT) patients with established chronic lung allograft dysfunction (CLAD). Methods: This retrospective study included LT patients in two reference LT units who started everolimus therapy to treat CLAD from October 2008 to October 2016.
Iturbe-Fernández D, de Pablo Gafas A, Mora Cuesta VM, Alonso Moralejo R, Quezada Loaiza CA, Pérez González V, López-Padilla D, Cifrián JM.   +7 more
europepmc   +6 more sources

ALEMTUZUMAB FOR CHRONIC LUNG ALLOGRAFT DYSFUNCTION [PDF]

Chest, 2020
SESSION TITLE: Transplantation Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: October 18-21, 2020 PURPOSE: Chronic lung allograft dysfunction (CLAD) remains the leading cause of long-term mortality after lung transplantation (LTX) with no proven therapeutic strategies except re-transplantation Anecdotal reports suggest a role for ...
Reda E. Girgis, Gayathri Sathiyamoorthy, Jennifer K. McDermott, Cameron Lawson, Anupam Kumar, Ryan Hadley, Marzia Leacche, Edward Murphy   +7 more
openalex   +2 more sources

Impact of Angiotensin Blockade on Development of Chronic Lung Allograft Dysfunction. [PDF]

J Pharm Pract, 2023
January SE, Hubbard J, Fester KA, Dubrawka CA, Vazquez Guillamet R, Kulkarni HS, Hachem RR.   +6 more
europepmc   +3 more sources

Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation. [PDF]

J Clin Invest
Kulkarni HS, Tague LK, Calabrese DR, Liao F, Liu Z, Garnica L, Shankar NR, Wu X, Kulkarni DH, Thapa A, Zhou D, Tao Y, Davis VE, Bernardt CT, Byers DE, Chen C, Huang HJ, Witt CA, Hachem RR, Kreisel D, Atkinson JP, Greenland JR, Gelman AE.   +22 more
europepmc   +3 more sources

Lung transplantation: Chronic allograft dysfunction and establishing immune tolerance [PDF]

Human Immunology, 2014
Despite significant medical advances since the advent of lung transplantation, improvements in long-term survival have been largely unrealized. Chronic lung allograft dysfunction, in particular obliterative bronchiolitis, is the primary limiting factor ...
Gracon, Adam S.A., Wilkes, David S.
core   +4 more sources

Chronic lung allograft dysfunction following lung transplantation: Challenges and solutions [PDF]

, 2014
Bradford C Bemiss, Chad A WittDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USAAbstract: Chronic rejection is a major cause of death after the first year ...
Bemiss, Bradford C., Witt, Chad A.
core   +5 more sources

Chronic Lung Allograft Dysfunction Is Associated with Significant Disability after Lung Transplantation-A Burden of Disease Analysis in 1025 Cases. [PDF]

Adv Respir Med, 2023
Diel R, Simon S, Gottlieb J.
europepmc   +3 more sources

Analysis of BAL extracellular vesicles unveils NF-κB activation at the onset of chronic lung allograft dysfunction. [PDF]

Clin Sci (Lond)
Storaci AM, de Filippo MR, Franzi S, Mansour N, Lopez G, Molisso MT, Zadra G, Brevi M, Gianazza E, Banfi C, Bianchi C, Garulli G, Mendogni P, Nosotti M, Blasi F, Morlacchi LC, Palleschi A, Vaira V.   +17 more
europepmc   +2 more sources