Medial Injury/Dysfunction Induced Granulation Tissue Repair is the Pathogenesis of Atherosclerosis [PDF]
arXiv, 2020 Atherosclerosis, a chronic lesion of vascular wall, remains a leading cause of death and loss of life years. Classical hypotheses for atherosclerosis are long-standing mainly to explain atherogenesis. Unfortunately, these hypotheses may not explain the variation in the susceptibility to atherosclerosis.
arxiv
Multimedia Respiratory Database (RespiratoryDatabase@TR): Auscultation Sounds and Chest X-rays [PDF]
Natural and Engineering Sciences, 2017, 2021 Auscultation is a method for diagnosis of especially internal medicine diseases such as cardiac, pulmonary and cardio-pulmonary by listening the internal sounds from the body parts. It is the simplest and the most common physical examination in the assessment processes of the clinical skills.
arxiv
Telomere Dysfunction Drives Chronic Lung Allograft Dysfunction Pathology [PDF]
, 2019 ABSTRACTRationaleTelomere dysfunction is associated with multiple fibrotic lung processes, including chronic lung allograft dysfunction (CLAD) which is a major limitation to long-term survival following lung transplantation. Although shorter donor telomere lengths are associated with an increased risk of CLAD, it is unknown whether short telomeres are ...
Naikawadi, Ram P. +7 more
openaire +2 more sources
Montelukast in chronic lung allograft dysfunction after lung transplantation
The Journal of Heart and Lung Transplantation, 2019 Chronic lung allograft dysfunction (CLAD) is a major cause of post‒lung transplant mortality, with limited medical treatment options. In this study we assessed the association of montelukast treatment with pulmonary function and outcome in lung transplant recipients with progressive CLAD.We performed a retrospective study of all lung transplant ...
Vos, Robin +28 more
openaire +4 more sources
Imaging indications and findings in evaluation of lung transplant graft dysfunction and rejection
Insights into Imaging, 2020 Lung transplantation is a treatment option in end-stage lung disease. Complications can develop along a continuum in the immediate or longer post-transplant period, including surgical and technical complications, primary graft dysfunction, rejection ...
Mnahi Bin Saeedan +3 more
doaj +1 more source
Frontiers in Immunology, 2023 IntroductionChronic lung allograft dysfunction (CLAD) is the main cause of the reduced survival of lung transplanted (LTx) patients. The possible role of immune checkpoint molecules in establishing tolerance has been scarcely investigated in the setting ...
Ilaria Righi +16 more
doaj +1 more source
Development of a Multi-Task Learning V-Net for Pulmonary Lobar Segmentation on Computed Tomography and Application to Diseased Lungs [PDF]
arXiv, 2021 Automated lobar segmentation allows regional evaluation of lung disease and is important for diagnosis and therapy planning. Advanced statistical workflows permitting such evaluation is a needed area within respiratory medicine; their adoption remains slow, with poor workflow accuracy. Diseased lung regions often produce high-density zones on CT images,
arxiv
Perioperative donor bone marrow infusion augments chimerism in heart and lung transplant recipients [PDF]
, 1995 Background.: We and others have demonstrated that a low level of donor cell chimerism was present for years after transplantation in tissues and peripheral blood of heart and lung recipients; it was associated, in the latter, with a lower incidence of ...
Abdul S. Rao +34 more
core +1 more source
Prediction of chronic lung allograft dysfunction: a systems medicine challenge [PDF]
European Respiratory Journal, 2014 The International Society for Heart and Lung Transplantation registry recorded that 3631 adult heart-lung transplants and 39 835 adult lung transplants have been performed in centres throughout the world up to 2012, establishing lung transplantation (LT) as the standard of care for selected patients with end-stage respiratory disease [1]. The long-term
Pison, Christophe +16 more
openaire +7 more sources
Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection. [PDF]
, 2019 BackgroundChronic lung allograft dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Because effective therapies are lacking, early identification and mitigation of risk factors is a pragmatic approach to improve ...
Belperio, John A +13 more
core +1 more source