Results 101 to 110 of about 37,459 (257)

Early Identification of Chronic Lung Allograft Dysfunction: The Need of Biomarkers [PDF]

Frontiers in Immunology, 2019
A growing number of patients with end-stage lung disease have benefited from lung transplantation (LT). Improvements in organ procurement, surgical techniques and intensive care management have greatly increased short-term graft survival. However, long-term outcomes remain limited, mainly due to the onset of chronic lung allograft dysfunction (CLAD ...
Adrien Tissot, Adrien Tissot, Richard Danger, Richard Danger, Johanna Claustre, Johanna Claustre, Antoine Magnan, Antoine Magnan, Antoine Magnan, Antoine Magnan, Sophie Brouard, Sophie Brouard   +11 more
openaire   +7 more sources

Respiratory metapneumoviral infection without co-infection in association with acute and chronic lung allograft dysfunction

Journal of Inflammation Research, 2015
Amrita DosanjhDepartment of Pediatrics, Rady Children’s Hospital, San Diego, CA, USABackground: Metapneumoviral respiratory infection is a community-acquired respiratory viral (CARV) infection. Lung transplantation recipients exposed to CARV are at
Dosanjh A
doaj  

Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation

ERJ Open Research, 2021
Surveillance after lung transplantation is critical to the detection of acute cellular rejection (ACR) and prevention of chronic lung allograft dysfunction (CLAD).
Kiran K. Khush, Iwijn De Vlaminck, Helen Luikart, David J. Ross, Mark R. Nicolls   +4 more
doaj   +1 more source

Recent advances in lung transplantation [version 1; referees: 2 approved]

F1000Research, 2018
Lung transplantation can improve quality of life and prolong survival for individuals with end-stage lung disease, and many advances in the realms of both basic science and clinical research aspects of lung transplantation have emerged over the past few ...
Keith C Meyer
doaj   +1 more source

Alemtuzumab as a Therapy for Chronic Lung Allograft Dysfunction in Lung Transplant Recipients With Short Telomeres

Frontiers in Immunology, 2020
Alemtuzumab, a monoclonal antibody targeting CD52 that causes lymphocyte apoptosis, is a form of advanced immunosuppression that is currently used as a therapy for refractory acute cellular rejection and chronic lung allograft dysfunction in lung ...
Anil J. Trindade, Anil J. Trindade, Anil J. Trindade, Tany Thaniyavarn, Tany Thaniyavarn, Keri Townsend, Robin Klasek, Karen P. Tsveybel, John C. Kennedy, John C. Kennedy, Hilary J. Goldberg, Hilary J. Goldberg, Souheil El-Chemaly, Souheil El-Chemaly   +13 more
doaj   +1 more source

Airway Telomere Length in Lung Transplant Recipients

Frontiers in Immunology, 2021
IntroductionChronic lung allograft dysfunction (CLAD) represents the major impediment to long term survival following lung transplantation. Donor and recipient telomere length have been shown to associate with lung transplant outcomes, including CLAD. In
John A. Mackintosh, Stephanie T. Yerkovich, Stephanie T. Yerkovich, Maxine E. Tan, Luke Samson, Peter MA Hopkins, Peter MA Hopkins, Daniel C. Chambers, Daniel C. Chambers   +8 more
doaj   +1 more source

U-Net-based Lung Thickness Map for Pixel-level Lung Volume Estimation of Chest X-rays [PDF]

arXiv, 2021
Purpose: We aimed to estimate the total lung volume (TLV) from real and synthetic frontal X-ray radiographs on a pixel level using lung thickness maps generated by a U-Net. Methods: 5,959 thorax X-ray computed tomography (CT) scans were retrieved from two publicly available datasets of the lung nodule analysis 2016 (n=656) and the RSNA pulmonary ...
arxiv  

Chronic lung allograft dysfunction: light at the end of the tunnel?

Current Opinion in Organ Transplantation, 2019
Purpose of review Chronic lung allograft dysfunction (CLAD) has been recently introduced as an umbrella-term encompassing all forms of chronic pulmonary function decline posttransplant with bronchiolitis obliterans syndrome and restrictive allograft syndrome as the most important subtypes. Differential diagnosis and management,
Verleden, Stijn E., Vos, Robin, Verleden, Geert M.   +2 more
openaire   +3 more sources

Lung volumes predict survival in patients with chronic lung allograft dysfunction [PDF]

European Respiratory Journal, 2017
Identification of disease phenotypes might improve the understanding of patients with chronic lung allograft dysfunction (CLAD). The aim of the study was to assess the impact of pulmonary restriction and air trapping by lung volume measurements at the onset of CLAD.A total of 396 bilateral lung transplant recipients were analysed.
Nikolaus Kneidinger, Katrin Milger, Silke Janitza, Felix Ceelen, Gabriela Leuschner, Julien Dinkel, Melanie Königshoff, Thomas Weig, René Schramm, Hauke Winter, Jürgen Behr, Claus Neurohr   +11 more
openaire   +3 more sources

A Lightweight CNN Model for Detecting Respiratory Diseases from Lung Auscultation Sounds using EMD-CWT-based Hybrid Scalogram [PDF]

arXiv, 2020
Listening to lung sounds through auscultation is vital in examining the respiratory system for abnormalities. Automated analysis of lung auscultation sounds can be beneficial to the health systems in low-resource settings where there is a lack of skilled physicians.
arxiv