Results 201 to 210 of about 24,300 (246)

Fibrotic progression from acute cellular rejection is dependent on secondary lymphoid organs in a mouse model of chronic lung allograft dysfunction. [PDF]

Am J Transplant
Mineura K, Tanaka S, Goda Y, Terada Y, Yoshizawa A, Umemura K, Sato A, Yamada Y, Yutaka Y, Ohsumi A, Nakajima D, Hamaji M, Mennju T, Kreisel D, Date H.   +14 more
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Antireflux surgery for prevention of chronic lung allograft dysfunction (CLAD) onset after lung transplantation: The earlier the better before CLAD onset? A single-center series of 284 patients. [PDF]

JHLT Open
Hamid A, Vallée A, Rong S, Boche O, De Miranda S, Beaumont-Azuar L, de Verdière SC, Grenet D, Stern M, Zuber B, Devaquet J, Fessler J, De Wolf J, Pricopi C, Glorion M, Sage E, Messika J, Magnan A, Parquin F, Picard C, Roux A, Brugière O.   +21 more
europepmc   +1 more source

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Chronic Lung Allograft Dysfunction

Thoracic Surgery Clinics, 2022
Chronic lung allograft dysfunction (CLAD) is a syndrome of progressive lung function decline, subcategorized into obstructive, restrictive, and mixed phenotypes. The trajectory of CLAD is variable depending on the phenotype, with restrictive and mixed phenotypes having more rapid progression and lower survival.
Aida, Venado, Jasleen, Kukreja, John R, Greenland   +2 more
openaire   +3 more sources

Chronic lung allograft dysfunction

Indian Journal of Thoracic and Cardiovascular Surgery, 2021
Lung transplantation remains the only cure for selected patients with advanced irreversible lung diseases. More than 4000 lung transplants are performed worldwide annually. In the last two decades, significant advances have been made in this arena, the most impactful being a modest but improved survival of the recipients.
Anupam Kumar, Puneet Singh Garcha
openaire   +3 more sources

Surgical therapy of chronic lung allograft dysfunction

Perspectives in Surgery, 2023
Lung transplantation has become a standardized and widely accepted treatment modality for selected end-stage lung diseases. Many factors influence the long-term survival of patients after lung transplantation. One of the most important is clearly the development of chronic lung allograft dysfunction (CLAD).
R, Novysedlák, J, Tavandžis, J, Balko, Z, Ozaniak Střížová, J, Vachtenheim, R, Lischke   +5 more
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Pharmacotherapy of chronic lung allograft dysfunction post lung transplantation

Clinical Transplantation, 2022
AbstractBackgroundChronic lung allograft dysfunction (CLAD) remains the primary cause of death in lung transplant recipients (LTRs) despite improvements in immunosuppression management. Despite advances in knowledge regarding the pathogenesis of CLAD, treatments that are currently available are usuallyineffective and delay progression of disease at ...
Rickey A. Evans, Krysta S. Walter, Leonard Jason Lobo, Raymond Coakley, Christina T. Doligalski   +4 more
openaire   +2 more sources

Chronic lung allograft dysfunction

Current Opinion in Organ Transplantation, 2015
Chronic lung allograft dysfunction (CLAD) was recently introduced as an overarching term covering different phenotypes of chronic allograft dysfunction, including obstructive CLAD (bronchiolitis obliterans syndrome), restrictive CLAD (restrictive allograft syndrome) and graft dysfunction due to causes not related to chronic rejection.
Robin, Vos, Stijn E, Verleden, Geert M, Verleden   +2 more
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Emerging biomarkers in chronic lung allograft dysfunction

Expert Review of Molecular Diagnostics, 2020
Introduction: Lung transplantation remains an important treatment for patients with end stage lung disease. Chronic lung allograft dysfunction (CLAD) remains the greatest limiting factor for long term survival. As the diagnosis of CLAD is based on pulmonary function tests, significant lung injury is required before a diagnosis is feasible, likely when ...
Osnat Shtraichman, Joshua M Diamond
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Chronic Lung Allograft Dysfunction: Evolving Concepts and Therapies

Seminars in Respiratory and Critical Care Medicine, 2021
AbstractThe primary factor that limits long-term survival after lung transplantation is chronic lung allograft dysfunction (CLAD). CLAD also impairs quality of life and increases the costs of medical care. Our understanding of CLAD continues to evolve. Consensus definitions of CLAD and the major CLAD phenotypes were recently updated and clarified, but ...
Olawale, Amubieya, Allison, Ramsey, Ariss, DerHovanessian, Gregory A, Fishbein, Joseph P, Lynch, John A, Belperio, S Samuel, Weigt   +6 more
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Update in Chronic Lung Allograft Dysfunction

Clinics in Chest Medicine, 2017
Chronic lung allograft dysfunction (CLAD) is the major limitation to posttransplant survival. This review highlights the evolving definition of CLAD, risk factors, treatment, and expected outcomes after the development of CLAD.
Rupal J, Shah, Joshua M, Diamond
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