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The diagnosis and management of chronic lung allograft dysfunction
Purpose of review Chronic lung allograft dysfunction (CLAD) remains a life-threatening complication following lung transplantation. Different CLAD phenotypes have recently been defined, based on the combination of pulmonary function testing and chest ...
G. Verleden+2 more
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Surgical therapy of chronic lung allograft dysfunction
Perspectives in Surgery, 2023Lung transplantation has become a standardized and widely accepted treatment modality for selected end-stage lung diseases. Many factors influence the long-term survival of patients after lung transplantation. One of the most important is clearly the development of chronic lung allograft dysfunction (CLAD).
R, Novysedlák+5 more
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Emerging biomarkers in chronic lung allograft dysfunction
Expert Review of Molecular Diagnostics, 2020Introduction: Lung transplantation remains an important treatment for patients with end stage lung disease. Chronic lung allograft dysfunction (CLAD) remains the greatest limiting factor for long term survival. As the diagnosis of CLAD is based on pulmonary function tests, significant lung injury is required before a diagnosis is feasible, likely when ...
Joshua M. Diamond+2 more
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Update in Chronic Lung Allograft Dysfunction
Clinics in Chest Medicine, 2017Chronic lung allograft dysfunction (CLAD) is the major limitation to posttransplant survival. This review highlights the evolving definition of CLAD, risk factors, treatment, and expected outcomes after the development of CLAD.
Rupal J. Shah, Joshua M. Diamond
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Chronic lung allograft dysfunction
Current Respiratory Care Reports, 2014The recognition that chronic graft dysfunction after lung transplantation is a heterogeneous phenomenon has led to the introduction of a new term: chronic lung allograft dysfunction (CLAD). An International Society for Heart and Lung Transplantation working group will determine a definition of CLAD in 2014.
Masaaki Sato, Masaaki Sato
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