Results 231 to 240 of about 37,459 (257)

Characterization Of Chronic Lung Allograft Dysfunction With Oscillometry

The Journal of Heart and Lung Transplantation, 2020
Summary of Objectives Chronic lung allograft dysfunction (CLAD) affects up to 70% of lung transplant (LTx) recipients and is the major impediment to long-term survival. CLAD is a retrospective diagnosis of exclusion when other causes for sustained drop of ≥20% of forced expiratory volume in 1s or forced vital capacity have been ruled out. No effective
R. Nadi, A. Vasileva, Clodagh M. Ryan, Jussi Tikkanen, Tereza Martinu, Q. Huang, Jun Wu, Shaf Keshavjee, Marcelo Cypel, J. Matelski, D. Abelson, Chung-Wai Chow, E. deHaas   +12 more
openaire   +2 more sources

Airway Alterations in Chronic Lung Allograft Dysfunction

The Journal of Heart and Lung Transplantation, 2014
s S105 M. Rivera-Otero, A. Salvador-Sanz. Cardiology Department. Hert Failure and Transplantation Unit, Hospital Universitari i Politecnic La Fe,
B. Vanaudenaerde, David Ruttens, Dragoş M. Vasilescu, James C. Hogg, Erik Verbeken, Stijn E. Verleden, D. Van Raemdonck, Geert Verleden, Marc Decramer, Joel D. Cooper, Stijn Willems, Jeroen Hostens, Benoît Rondelet, Christiane Knoop, Johny Verschakelen, John E. McDonough, Elly Vandermeulen, Robin Vos   +17 more
openaire   +2 more sources

Noninvasive methods for detection of chronic lung allograft dysfunction in lung transplantation

Transplantation Reviews, 2020
Lung transplantation (LTx) is the only therapeutic option for end-stage lung diseases. Chronic lung allograft dysfunction (CLAD), which manifests as airflow restriction and/or obstruction, is the primary factor limiting the long-term survival of patients after surgery.
Dong Tian, Dong Tian, Dong Tian, Hong-Ying Wen, Heng Huang   +4 more
openaire   +2 more sources

A new classification system for chronic lung allograft dysfunction

The Journal of Heart and Lung Transplantation, 2014
Although survival after lung transplantation has improved significantly during the last decade, chronic rejection is thought to be the major cause of late mortality. The physiologic hallmark of chronic rejection has been a persistent fall in forced expiratory volume in 1 second associated with an obstructive ventilatory defect, for which the term ...
Verleden GM, Raghu G, Meyer KC, Glanville AR, Corris P   +4 more
openaire   +4 more sources

Chronic lung allograft dysfunction after lung transplantation: the moving target

General Thoracic and Cardiovascular Surgery, 2012
Chronic lung allograft dysfunction is a major challenge in long-term management of lung transplant recipients. Both alloimmune-dependent factors (rejection) and alloimmune-independent factors contribute to the development of chronic lung allograft dysfunction. Thus, use of the term "chronic rejection" tends to be intentionally avoided among specialists
Masaaki Sato, Masaaki Sato
openaire   +2 more sources

Chronic Lung Allograft Dysfunction: Phenotypes and the Future

2018
Chronic lung allograft dysfunction (CLAD, an umbrella term which encompasses two subtypes—restrictive allograft syndrome (RAS) and bronchiolitis obliterans syndrome (BOS)) remains the major barrier to long-term survival after lung transplantation. CLAD affects approximately 10% of patients each year and has proven a particularly difficult problem to ...
openaire   +3 more sources

Chronic lung allograft dysfunction

Transplantation Reviews, 1998
Hélène Levrey, Marshall I. Hertz
openaire   +2 more sources

Extreme elevations of donor-derived cell-free DNA increases the risk of chronic lung allograft dysfunction and death, even without clinical manifestations of disease.

The Journal of Heart and Lung Transplantation
M. Keller, David Newman, Muhtadi Alnababteh, L. Ponor, Pali Shah, Joby Matthews, H. Kong, T. Andargie, W. Park, A. Charya, H. Luikart, S. Aryal, Steven D. Nathan, J. Orens, K. Khush, M. Jang, S. Agbor-Enoh   +16 more
semanticscholar   +1 more source

The CD8+ T cell content of transbronchial biopsies from patients with a first episode of clinically stable grade A1 cellular rejection is associated with future chronic lung allograft dysfunction.

The Journal of Heart and Lung Transplantation
S. Beber, S. Moshkelgosha, Matthew White, Z. Guan, M. Cheung, David Hedley, L. Levy, J. Samuels, B. Renaud-Picard, David Hwang, T. Martinu, S. Juvet   +11 more
semanticscholar   +1 more source

Small airway brush gene expression predicts chronic lung allograft dysfunction and mortality.

The Journal of Heart and Lung Transplantation
R. Mohanty, K. Moghbeli, J. Singer, D. Calabrese, S. Hays, C. Iasella, S. Lieber, L. Leard, Rupal J. Shah, A. Venado, M. Kleinhenz, Jeffery A. Golden, T. Martinu, Christina Love, R. Ward, C. Langelier, J. McDyer, J. Greenland   +17 more
semanticscholar   +1 more source