Results 21 to 30 of about 37,459 (257)

Unique Changes in the Lung Microbiome following the Development of Chronic Lung Allograft Dysfunction. [PDF]

Microorganisms
The importance of lung microbiome changes in developing chronic lung allograft dysfunction (CLAD) after lung transplantation is poorly understood. The lung microbiome–immune interaction may be critical in developing CLAD.
Yu Y, Kim YH, Cho WH, Kim D, So MW, Son BS, Yeo HJ.   +6 more
europepmc   +2 more sources

The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. [PDF]

Transplantation, 2023
Background. After lung transplantation, both frailty and chronic lung allograft dysfunction (CLAD) commonly develop, and when they do, are associated with poorer outcomes.
Singer JP, Gao Y, Huang CY, Kordahl RC, Sriram A, Hays SR, Kukreja J, Venado A, Calabrese DR, Greenland JR.   +9 more
europepmc   +2 more sources

Chronic lung allograft dysfunction following lung transplantation: challenges and solutions [PDF]

Transplant Research and Risk Management, 2014
Bradford C Bemiss, Chad A WittDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USAAbstract: Chronic rejection is a major cause of death after the first year ...
Bemiss BC, Witt CA
doaj   +4 more sources

Oesophageal stasis is a risk factor for chronic lung allograft dysfunction and allograft failure in lung transplant recipients. [PDF]

ERJ Open Res, 2023
Background Morbidity and mortality in lung transplant recipients are often triggered by recurrent aspiration events, potentiated by oesophageal and gastric disorders. Previous small studies have shown conflicting associations between oesophageal function
Ramendra R, Fernández-Castillo JC, Huszti E, Ghany R, Aversa M, Havlin J, Riddell P, Chaparro CM, Singer LG, Liu L, Keshavjee S, Yeung JC, Martinu T.   +12 more
europepmc   +2 more sources

Potential novel biomarkers for chronic lung allograft dysfunction and azithromycin responsive allograft dysfunction [PDF]

Scientific Reports, 2021
Chronic Lung Allograft Dysfunction (CLAD), manifesting as Bronchiolitis Obliterans Syndrome (BOS) or Restrictive Allograft Syndrome (RAS), is the main reason for adverse long-term outcome after Lung Transplantation (LTX).
Cecilia Veraar, Jonathan Kliman, Alberto Benazzo, Felicitas Oberndorfer, Maria Laggner, Philipp Hacker, Thomas Raunegger, Stefan Janik, Peter Jaksch, Walter Klepetko, Hendrik J. Ankersmit, Bernhard Moser   +11 more
doaj   +4 more sources

Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK). [PDF]

BMJ Open Respir Res
Background Long-term survival after lung transplantation is limited compared with other organ transplants. The main cause is development of progressive immune-mediated damage to the lung allograft.
Fisher AJ, White M, Goudie N, Kershaw A, Phillipson J, Bardgett M, Lally J, Bevin-Nicholls A, Chadwick T, Bryant A, Russell S, Smith H, Frisby L, Errington R, Carby M, Thompson R, Santhanakrishnan K, Parmar J, Lordan JL, Vale L, Hancock H, Exley C, Gennery AR, Wason JM.   +23 more
europepmc   +2 more sources

Lung Transplantation: CT Assessment of Chronic Lung Allograft Dysfunction (CLAD) [PDF]

Diagnostics, 2021
Chronic lung allograft rejection remains one of the major causes of morbi-mortality after lung transplantation. The term Chronic Lung Allograft Dysfunction (CLAD) has been proposed to describe the different processes that lead to a significant and ...
Anne-Laure Brun, Marie-Laure Chabi, Clément Picard, François Mellot, Philippe A. Grenier   +4 more
doaj   +3 more sources

Late-Onset Exudative Pleural Effusions Without Concomitant Airway Obstruction or Lung Parenchymal Abnormalities: A Novel Presentation of Chronic Lung Allograft Dysfunction. [PDF]

Transpl Int
Restrictive allograft syndrome (RAS) is an aggressive variant of CLAD characterized by progressive restrictive ventilatory decline and persistent pleuro-parenchymal changes that can be seen on chest CT.
Sindu D, Bansal S, Buddhdev B, McAnally K, Mohamed H, Walia R, Mohanakumar T, Tokman S.   +7 more
europepmc   +2 more sources

Changes in HCMV immune cell frequency and phenotype are associated with chronic lung allograft dysfunction. [PDF]

Front Immunol, 2023
Background Human cytomegalovirus (HCMV) infection is common and often severe in lung transplant recipients (LTRs), and it is a risk factor associated with chronic lung allograft dysfunction (CLAD).
Rousselière A, Delbos L, Foureau A, Reynaud-Gaubert M, Roux A, Demant X, Le Pavec J, Kessler R, Mornex JF, Messika J, Falque L, Le Borgne A, Boussaud V, Tissot A, Hombourger S, Bressollette-Bodin C, Charreau B.   +16 more
europepmc   +2 more sources

Donor-derived cell-free DNA in chronic lung allograft dysfunction phenotypes: a pilot study [PDF]

Frontiers in Transplantation
Long-term survival after lung transplantation is limited due to chronic lung allograft dysfunction (CLAD), which encompasses two main phenotypes: bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS).
H. Beeckmans, A. Pagliazzi, P. Kerckhof, R. Hofkens, F. Debackere, A. Zajacova, S. Bos, S. Bos, B. M. Vanaudenaerde, H. de Loor, M. Naesens, M. Naesens, R. Vos, R. Vos   +13 more
doaj   +2 more sources