Elastocapillary network model of inhalation [PDF]
The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and overall air flow into the lungs.
arxiv +1 more source
Antibody-Mediated Rejection and Sponge Effect in a Redo Lung Transplant Recipient
Long-term survival after lung transplant remains severely limited by chronic lung allograft dysfunction. Antibody-mediated rejection of lung transplant allografts is usually caused by donor-specific antibodies (DSAs) directed toward donor human leukocyte
Ashwini Arjuna+8 more
doaj +1 more source
The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A+18 more
core +1 more source
Lung Transplantation and the Era of the Sensitized Patient
Long term outcomes in lung transplant are limited by the development of chronic lung allograft dysfunction (CLAD). Within the past several decades, antibody-mediated rejection (AMR) has been recognized as a risk factor for CLAD.
Katherine A. Young+4 more
doaj +1 more source
Chronic Rejection after Lung Transplantation [PDF]
A new classification system for chronic rejection in lung transplantation was recently proposed. Chronic lung allograft dysfunction (CLAD) is regarded as chronic rejection after excluding other causes of allograft dysfunction.
김송이
core +1 more source
Medical Complications of Lung Transplantation
Lung transplantation (LT) is now considered as an effective treatment option for end-stage lung diseases that improves the short and long-term survival rates and quality of life.
Moo Suk Park
doaj +1 more source
MiR-21 in Lung Transplant Recipients With Chronic Lung Allograft Dysfunction [PDF]
Background: Micro-RNA-21 (miR-21) is a post-translational regulator involved in epithelial-to-mesenchymal transition (EMT). Since EMT is thought to contribute to chronic lung allograft dysfunction (CLAD), we aimed to characterize miR-21 expression and distinct EMT markers in CLAD.Methods: Expression of miR-21, vimentin, Notch intracellular domain (NICD)
Miyahara, Naofumi+9 more
openaire +2 more sources
A Flexible Joint Model for Multiple Longitudinal Biomarkers and A Time-to-Event Outcome: With Applications to Dynamic Prediction Using Highly Correlated Biomarkers [PDF]
In biomedical studies it is common to collect data on multiple biomarkers during study follow-up for dynamic prediction of a time-to-event clinical outcome. The biomarkers are typically intermittently measured, missing at some event times, and may be subject to high biological variations, which cannot be readily used as time-dependent covariates in a ...
arxiv
Liver transplantation for alcoholic cirrhosis: Long term follow-up and impact of disease recurrence [PDF]
Background. Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse.
Andrea M. DiMartini+71 more
core +1 more source
Host–Pathogen Interactions and Chronic Lung Allograft Dysfunction [PDF]
Lung transplantation is now considered to be a therapeutic option for patients with advanced-stage lung diseases. Unfortunately, due to post-transplant complications, both infectious and noninfectious, it is only a treatment and not a cure. Infections (e.g., bacterial, viral, and fungal) in the immunosuppressed lung transplant recipient are a common ...
Belperio, John+2 more
openaire +5 more sources