Results 81 to 90 of about 37,459 (257)

Infectious Triggers of Chronic Lung Allograft Dysfunction [PDF]

Current Infectious Disease Reports, 2016
Survival after lung transplantation is limited in large part due to the high incidence of chronic rejection, known as chronic lung allograft dysfunction (CLAD). Pulmonary infections are a frequent complication in lung transplant recipients, due both to immunosuppressive medications and constant exposure of the lung allograft to the external environment
openaire   +3 more sources

Respiratory tract microbiome modifications after lung transplantation and its impact in CLAD [PDF]

, 2022
Survival after lung transplantation is limited in large part due to the high incidence of chronic lung allograft dysfunction (CLAD). Infection is a recognized risk factor for the development of CLAD, and both acute infection and chronic lung allograft ...
Gabaldón, Toni, Khannous-Lleiffe
core  

Lung transplantation: Chronic allograft dysfunction and establishing immune tolerance [PDF]

, 2014
Despite significant medical advances since the advent of lung transplantation, improvements in long-term survival have been largely unrealized. Chronic lung allograft dysfunction, in particular obliterative bronchiolitis, is the primary limiting factor ...
Gracon, Adam S.A., Wilkes, David S.
core   +1 more source

Using a combination of biomarkers to monitor allograft dysfunction in lung transplant recipients

Frontiers in Transplantation
Allograft dysfunction is a major limitation of survival in organ transplant recipients including those who have received lung transplantation. Early detection of allograft dysfunction is thus crucial to improve outcomes in these patients.
Zein Kattih, Shambhu Aryal
doaj   +1 more source

Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]

, 2011
Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh, Roedder, Silke, Sarwal, Minnie M, Vitalone, Matthew   +3 more
core   +3 more sources

A urinary Common Rejection Module (uCRM) score for non-invasive kidney transplant monitoring. [PDF]

, 2019
A Common Rejection Module (CRM) consisting of 11 genes expressed in allograft biopsies was previously reported to serve as a biomarker for acute rejection (AR), correlate with the extent of graft injury, and predict future allograft damage.
Bestard, Oriol, Damm, Izabella, Geraedts, Anna CM, Hsieh, Szu-Chuan, Liberto, Juliane M, Sarwal, Minnie M, Schroeder, Andrew, Sigdel, Tara K, Yang, Joshua YC   +8 more
core   +2 more sources

Human neutrophil peptide in lung chronic allograft dysfunction [PDF]

Biomarkers, 2011
Our previous case-control study identified human neutrophil peptide (HNP) as a potential biomarker for bronchiolitis obliterans syndrome (BOS) in lung transplant recipients.To prospectively validate HNP as a biomarker for BOS.HNP was measured by ELISA in bronchoalveolar lavage (BAL) fluid in lung transplant recipients.The first HNP measurement after ...
Chris H. Wendt, Cavan S. Reilly, Trisha Becker, Marshall I. Hertz, Tereza Cervenka   +4 more
openaire   +3 more sources

Monitoring regulatory T cells as a prognostic marker in lung transplantation

Frontiers in Immunology, 2023
Lung transplantation is the major surgical procedure, which restores normal lung functioning and provides years of life for patients suffering from major lung diseases. Lung transplant recipients are at high risk of primary graft dysfunction, and chronic
Mohammad Afzal Khan, Christine L. Lau, Alexander Sasha Krupnick   +2 more
doaj   +1 more source

Radiological findings of complications after lung transplantation

Insights into Imaging, 2018
Complications following lung transplantation may impede allograft function and threaten patient survival. The five main complications after lung transplantation are primary graft dysfunction, post-surgical complications, alloimmune responses, infections,
Céline Habre, Paola M. Soccal, Frédéric Triponez, John-David Aubert, Thorsten Krueger, Steve P. Martin, Joanna Gariani, Jean-Claude Pache, Frédéric Lador, Xavier Montet, Anne-Lise Hachulla   +10 more
doaj   +1 more source

Mesenchymal Stromal Cell Therapy in Lung Transplantation

Bioengineering, 2023
Lung transplantation is often the only viable treatment option for a patient with end-stage lung disease. Lung transplant results have improved substantially over time, but ischemia-reperfusion injury, primary graft dysfunction, acute rejection, and ...
Antti I. Nykänen, Mingyao Liu, Shaf Keshavjee   +2 more
doaj   +1 more source